IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on <sup>18</sup>F-FDG PET/CT
We report a case of a 73-year-old man with minimally invasive lung adenocarcinoma, post-resection, evaluated with <sup>18</sup>F-FDG PET/CT for suspected disease progression. Imaging showed increased FDG uptake in the right lower lung mass and systemic lymphadenopathy (mediastinal, supra...
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MDPI AG
2024-12-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/15/1/41 |
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| author | Ting-Chun Tseng Hung-Pin Chan Daniel Hueng-Yuan Shen Chang-Chung Lin |
| author_facet | Ting-Chun Tseng Hung-Pin Chan Daniel Hueng-Yuan Shen Chang-Chung Lin |
| author_sort | Ting-Chun Tseng |
| collection | DOAJ |
| description | We report a case of a 73-year-old man with minimally invasive lung adenocarcinoma, post-resection, evaluated with <sup>18</sup>F-FDG PET/CT for suspected disease progression. Imaging showed increased FDG uptake in the right lower lung mass and systemic lymphadenopathy (mediastinal, supraclavicular, axillary, paraaortic, and iliac regions). The appearance of a stable lymph node and a clinical history of IgG4 lymphadenopathy suggested an inflammatory process, although malignancy in the lung mass and mediastinal nodes could not be excluded. Lobectomy confirmed the presence of lung adenocarcinoma, while radical lymph node dissection identified IgG4-related lymphadenopathy without metastasis. This case underscores the need for considering differential diagnosis of PET-positive lymphadenopathy, especially in patients with comorbid conditions that mimic or coexist with malignancy. |
| format | Article |
| id | doaj-art-f460259950d14d2891ea9fb92dc01fc7 |
| institution | Kabale University |
| issn | 2075-4418 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj-art-f460259950d14d2891ea9fb92dc01fc72025-01-10T13:16:32ZengMDPI AGDiagnostics2075-44182024-12-011514110.3390/diagnostics15010041IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on <sup>18</sup>F-FDG PET/CTTing-Chun Tseng0Hung-Pin Chan1Daniel Hueng-Yuan Shen2Chang-Chung Lin3Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, TaiwanDepartment of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, TaiwanDepartment of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, TaiwanDepartment of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, TaiwanWe report a case of a 73-year-old man with minimally invasive lung adenocarcinoma, post-resection, evaluated with <sup>18</sup>F-FDG PET/CT for suspected disease progression. Imaging showed increased FDG uptake in the right lower lung mass and systemic lymphadenopathy (mediastinal, supraclavicular, axillary, paraaortic, and iliac regions). The appearance of a stable lymph node and a clinical history of IgG4 lymphadenopathy suggested an inflammatory process, although malignancy in the lung mass and mediastinal nodes could not be excluded. Lobectomy confirmed the presence of lung adenocarcinoma, while radical lymph node dissection identified IgG4-related lymphadenopathy without metastasis. This case underscores the need for considering differential diagnosis of PET-positive lymphadenopathy, especially in patients with comorbid conditions that mimic or coexist with malignancy.https://www.mdpi.com/2075-4418/15/1/41FDGPET/CTIgG4-related lymphadenopathylung cancer |
| spellingShingle | Ting-Chun Tseng Hung-Pin Chan Daniel Hueng-Yuan Shen Chang-Chung Lin IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on <sup>18</sup>F-FDG PET/CT Diagnostics FDG PET/CT IgG4-related lymphadenopathy lung cancer |
| title | IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on <sup>18</sup>F-FDG PET/CT |
| title_full | IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on <sup>18</sup>F-FDG PET/CT |
| title_fullStr | IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on <sup>18</sup>F-FDG PET/CT |
| title_full_unstemmed | IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on <sup>18</sup>F-FDG PET/CT |
| title_short | IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on <sup>18</sup>F-FDG PET/CT |
| title_sort | igg4 related lymphadenopathy mimicking mediastinal lymph node metastasis of lung cancer on sup 18 sup f fdg pet ct |
| topic | FDG PET/CT IgG4-related lymphadenopathy lung cancer |
| url | https://www.mdpi.com/2075-4418/15/1/41 |
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