Petroselinic Acid from Apiaceae Family Plants Ameliorates Autoimmune Disorders Through Suppressing Cytosolic-Nucleic-Acid-Mediated Type I Interferon Signaling

Petroselinic Acid from Apiaceae Family Plants Ameliorates Autoimmune Disorders Through Suppressing Cytosolic-Nucleic-Acid-Mediated Type I Interferon Signaling

The recognition of cytosolic nucleic acids is a critical step in the host immune response against danger signals, such as molecular patterns from pathogens or tissue damage. Nonetheless, over-reactivity to self-nucleic acids leads to the sustained production of type I interferon (IFN), mediated eith...

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Main Authors: Yue Guo, Yun-Ying Wang, Yao Wang, Yan-Hong Liu, Jia-Yu Liu, Yan-Yan Shen, Ai-Ping Cao, Rui-Bo Wang, Bo-Yang Xie, Xin Pan, Ai-Ling Li, Tao Zhou, Na Wang, Qing Xia, Wei-Na Zhang
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomolecules
Subjects:
petroselinic acid
Apiaceae family plants
type I interferon
autoimmune disease
Online Access:https://www.mdpi.com/2218-273X/15/3/329
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