Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods: Focus on potential gene signatures and drugs for dementia

Untangling the complex mechanisms associated with Alzheimer's disease in elderly patients using high-throughput RNA sequencing data and next-generation knowledge discovery methods: Focus on potential gene signatures and drugs for dementia

Objectives: Alzheimer's disease (AD) is a complex neurodegenerative disorder that primarily affects elderly individuals. This study aimed to elucidate the intricate mechanisms underlying AD in elderly patients compared with healthy aged individuals using high-throughput RNA sequencing (RNA-seq)...

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Bibliographic Details
Main Authors: Hind A. Alkhatabi, Peter Natesan Pushparaj
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Alzheimer's disease
Dementia
GREIN
ExpressAnalyst
RNA sequencing
Gene set enrichment analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024172970
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