Malignant perforation of sigmoid colon in long-standing ulcerative colitis
Chronic ulcerative colitis (UC) is a risk factor for malignancy in long-term disease process. Obstruction, perforation, and hemorrhage are the possible emergency situations in colorectal malignancy. A 68-year-old male with chronic UC for 18 years with steroid-dependent disease (on 10 mg prednisolone...
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| Language: | English |
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SAGE Publishing
2020-01-01
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| Series: | Apollo Medicine |
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| Online Access: | http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2020;volume=17;issue=1;spage=46;epage=49;aulast=Adithya |
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| author | G K Adithya Varun Madaan Rigved Gupta Satya Prakash Jindal Deepak Govil |
| author_facet | G K Adithya Varun Madaan Rigved Gupta Satya Prakash Jindal Deepak Govil |
| author_sort | G K Adithya |
| collection | DOAJ |
| description | Chronic ulcerative colitis (UC) is a risk factor for malignancy in long-term disease process. Obstruction, perforation, and hemorrhage are the possible emergency situations in colorectal malignancy. A 68-year-old male with chronic UC for 18 years with steroid-dependent disease (on 10 mg prednisolone daily) presented with acute pain abdomen with distention not passing stool or flatus for 2 days. The patient was diagnosed to have perforation of colon secondary to rectosigmoid malignancy. Following the adjuvant therapy, the patient denied any definitive surgery and opted to stay on a colorectal cancer surveillance program. At present, the patient's positron emission tomography/computed tomography shows pelvic, liver surface, and small bowel deposits, suggestive of recurrence or metastasis. This case report is discussed to emphasize the importance of aggressive surgical treatment in long-term steroid-dependent disease and poor prognosis of perforated malignancy irrespective of pathological staging. |
| format | Article |
| id | doaj-art-f41e9396047f4220bced5c4f889b07f4 |
| institution | Kabale University |
| issn | 0976-0016 2213-3682 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Apollo Medicine |
| spelling | doaj-art-f41e9396047f4220bced5c4f889b07f42025-01-02T07:09:54ZengSAGE PublishingApollo Medicine0976-00162213-36822020-01-01171464910.4103/am.am_31_19Malignant perforation of sigmoid colon in long-standing ulcerative colitisG K AdithyaVarun MadaanRigved GuptaSatya Prakash JindalDeepak GovilChronic ulcerative colitis (UC) is a risk factor for malignancy in long-term disease process. Obstruction, perforation, and hemorrhage are the possible emergency situations in colorectal malignancy. A 68-year-old male with chronic UC for 18 years with steroid-dependent disease (on 10 mg prednisolone daily) presented with acute pain abdomen with distention not passing stool or flatus for 2 days. The patient was diagnosed to have perforation of colon secondary to rectosigmoid malignancy. Following the adjuvant therapy, the patient denied any definitive surgery and opted to stay on a colorectal cancer surveillance program. At present, the patient's positron emission tomography/computed tomography shows pelvic, liver surface, and small bowel deposits, suggestive of recurrence or metastasis. This case report is discussed to emphasize the importance of aggressive surgical treatment in long-term steroid-dependent disease and poor prognosis of perforated malignancy irrespective of pathological staging.http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2020;volume=17;issue=1;spage=46;epage=49;aulast=Adithyachronic ulcerative colitisperforated colonic malignancysteroid-dependent ulcerative colitis |
| spellingShingle | G K Adithya Varun Madaan Rigved Gupta Satya Prakash Jindal Deepak Govil Malignant perforation of sigmoid colon in long-standing ulcerative colitis Apollo Medicine chronic ulcerative colitis perforated colonic malignancy steroid-dependent ulcerative colitis |
| title | Malignant perforation of sigmoid colon in long-standing ulcerative colitis |
| title_full | Malignant perforation of sigmoid colon in long-standing ulcerative colitis |
| title_fullStr | Malignant perforation of sigmoid colon in long-standing ulcerative colitis |
| title_full_unstemmed | Malignant perforation of sigmoid colon in long-standing ulcerative colitis |
| title_short | Malignant perforation of sigmoid colon in long-standing ulcerative colitis |
| title_sort | malignant perforation of sigmoid colon in long standing ulcerative colitis |
| topic | chronic ulcerative colitis perforated colonic malignancy steroid-dependent ulcerative colitis |
| url | http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2020;volume=17;issue=1;spage=46;epage=49;aulast=Adithya |
| work_keys_str_mv | AT gkadithya malignantperforationofsigmoidcoloninlongstandingulcerativecolitis AT varunmadaan malignantperforationofsigmoidcoloninlongstandingulcerativecolitis AT rigvedgupta malignantperforationofsigmoidcoloninlongstandingulcerativecolitis AT satyaprakashjindal malignantperforationofsigmoidcoloninlongstandingulcerativecolitis AT deepakgovil malignantperforationofsigmoidcoloninlongstandingulcerativecolitis |