Characterization and Nutritional Intervention Effects of <i>Canna edulis</i> Type 5 Resistant Starch in Hyperlipidemia Mice
Numerous reports have indicated that the type 3 resistant starch (RS3) derived from <i>Canna edulis</i> can regulate lipid metabolism. However, it remains unclear whether the type 5 resistant starch (RS5) exhibits similar effects. In this study, RS5 was prepared from <i>Canna eduli...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
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| Series: | Foods |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2304-8158/14/1/92 |
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| Summary: | Numerous reports have indicated that the type 3 resistant starch (RS3) derived from <i>Canna edulis</i> can regulate lipid metabolism. However, it remains unclear whether the type 5 resistant starch (RS5) exhibits similar effects. In this study, RS5 was prepared from <i>Canna edulis</i> native starch and lauric acid through a hydrothermal method for the first time, and its nutritional intervention effects on hyperlipidemia in mice were investigated. The Canna edulis type 5 resistant starch (Ce-RS5) prepared using <i>Canna edulis</i> native starch and lauric acid exhibited a high compound index and resistant starch content, along with decreased swelling power and enhanced starch granule stability. The crystallinity of Ce-RS5 was decreased, and its crystal structure displayed a B+V pattern. Microscopically, the surface appeared rough with deepened grooves, and the granules were loose. Feeding mice with 1.5 g/kg and 3 g/kg of Ce-RS5 significantly reduced their body weight, positively regulated their blood lipid levels, and improved liver damage and fat accumulation. Additionally, Ce-RS5 promoted the abundance of beneficial gut bacteria, such as <i>norank_f_Muribaculaceae</i>, and inhibited the abundance of harmful bacteria like <i>Colidextribacter.</i> This study provides the first evidence of the hypolipidemic and weight loss effects of Ce-RS5 in hyperlipidemia mice. |
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| ISSN: | 2304-8158 |