Syncopal reactions in blood donors: Pathophysiology, clinical course, and features

Vasovagal syncope (VVS) in donors is a transient loss of consciousness due to short-term global cerebral hypoperfusion, which has a rapid onset and has complete spontaneous recovery. VVS may be triggered by pain, fear, anxiety, or emotional upset and loss of blood perse. It is an exaggeration of an...

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Main Authors: Abhishekh Basavarajegowda, Y. C. Nalini
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Asian Journal of Transfusion Science
Subjects:
Online Access:https://journals.lww.com/10.4103/ajts.ajts_167_21
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author Abhishekh Basavarajegowda
Y. C. Nalini
author_facet Abhishekh Basavarajegowda
Y. C. Nalini
author_sort Abhishekh Basavarajegowda
collection DOAJ
description Vasovagal syncope (VVS) in donors is a transient loss of consciousness due to short-term global cerebral hypoperfusion, which has a rapid onset and has complete spontaneous recovery. VVS may be triggered by pain, fear, anxiety, or emotional upset and loss of blood perse. It is an exaggeration of an adaptive response meant to assist in reducing the amount of bleeding/loss of blood. The four major components necessary for rapid cardiovascular adjustments to supine or upright posture, otherwise called orthostasis, are the autonomic nervous system, adequate blood volume, and intact skeletal and respiratory muscle pumps. The taxing of these autoregulatory mechanisms and their inability to compensate sufficiently results in VVS. VVR episodes can be described in 3 phases; Presyncope, Syncope, and Postsyncope. The actual syncope generally lasts for <15 s, comprising staring, muscle jerks, eye deviation/rolling, sometimes incontinence, loss of consciousness, gasping, snoring, apnea, inability to move/react, etc., The postsyncopal phase is the longest, which is generally manifested as fatigue.
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spelling doaj-art-f3fa4c1ff56b4c328b85138572e7a0b62025-01-08T09:09:58ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652024-12-0118229630210.4103/ajts.ajts_167_21Syncopal reactions in blood donors: Pathophysiology, clinical course, and featuresAbhishekh BasavarajegowdaY. C. NaliniVasovagal syncope (VVS) in donors is a transient loss of consciousness due to short-term global cerebral hypoperfusion, which has a rapid onset and has complete spontaneous recovery. VVS may be triggered by pain, fear, anxiety, or emotional upset and loss of blood perse. It is an exaggeration of an adaptive response meant to assist in reducing the amount of bleeding/loss of blood. The four major components necessary for rapid cardiovascular adjustments to supine or upright posture, otherwise called orthostasis, are the autonomic nervous system, adequate blood volume, and intact skeletal and respiratory muscle pumps. The taxing of these autoregulatory mechanisms and their inability to compensate sufficiently results in VVS. VVR episodes can be described in 3 phases; Presyncope, Syncope, and Postsyncope. The actual syncope generally lasts for <15 s, comprising staring, muscle jerks, eye deviation/rolling, sometimes incontinence, loss of consciousness, gasping, snoring, apnea, inability to move/react, etc., The postsyncopal phase is the longest, which is generally manifested as fatigue.https://journals.lww.com/10.4103/ajts.ajts_167_21blood donationemotional syncopepathophysiologyvasovagal syncope
spellingShingle Abhishekh Basavarajegowda
Y. C. Nalini
Syncopal reactions in blood donors: Pathophysiology, clinical course, and features
Asian Journal of Transfusion Science
blood donation
emotional syncope
pathophysiology
vasovagal syncope
title Syncopal reactions in blood donors: Pathophysiology, clinical course, and features
title_full Syncopal reactions in blood donors: Pathophysiology, clinical course, and features
title_fullStr Syncopal reactions in blood donors: Pathophysiology, clinical course, and features
title_full_unstemmed Syncopal reactions in blood donors: Pathophysiology, clinical course, and features
title_short Syncopal reactions in blood donors: Pathophysiology, clinical course, and features
title_sort syncopal reactions in blood donors pathophysiology clinical course and features
topic blood donation
emotional syncope
pathophysiology
vasovagal syncope
url https://journals.lww.com/10.4103/ajts.ajts_167_21
work_keys_str_mv AT abhishekhbasavarajegowda syncopalreactionsinblooddonorspathophysiologyclinicalcourseandfeatures
AT ycnalini syncopalreactionsinblooddonorspathophysiologyclinicalcourseandfeatures