Syncopal reactions in blood donors: Pathophysiology, clinical course, and features
Vasovagal syncope (VVS) in donors is a transient loss of consciousness due to short-term global cerebral hypoperfusion, which has a rapid onset and has complete spontaneous recovery. VVS may be triggered by pain, fear, anxiety, or emotional upset and loss of blood perse. It is an exaggeration of an...
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Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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Series: | Asian Journal of Transfusion Science |
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Online Access: | https://journals.lww.com/10.4103/ajts.ajts_167_21 |
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author | Abhishekh Basavarajegowda Y. C. Nalini |
author_facet | Abhishekh Basavarajegowda Y. C. Nalini |
author_sort | Abhishekh Basavarajegowda |
collection | DOAJ |
description | Vasovagal syncope (VVS) in donors is a transient loss of consciousness due to short-term global cerebral hypoperfusion, which has a rapid onset and has complete spontaneous recovery. VVS may be triggered by pain, fear, anxiety, or emotional upset and loss of blood perse. It is an exaggeration of an adaptive response meant to assist in reducing the amount of bleeding/loss of blood. The four major components necessary for rapid cardiovascular adjustments to supine or upright posture, otherwise called orthostasis, are the autonomic nervous system, adequate blood volume, and intact skeletal and respiratory muscle pumps. The taxing of these autoregulatory mechanisms and their inability to compensate sufficiently results in VVS. VVR episodes can be described in 3 phases; Presyncope, Syncope, and Postsyncope. The actual syncope generally lasts for <15 s, comprising staring, muscle jerks, eye deviation/rolling, sometimes incontinence, loss of consciousness, gasping, snoring, apnea, inability to move/react, etc., The postsyncopal phase is the longest, which is generally manifested as fatigue. |
format | Article |
id | doaj-art-f3fa4c1ff56b4c328b85138572e7a0b6 |
institution | Kabale University |
issn | 0973-6247 1998-3565 |
language | English |
publishDate | 2024-12-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Asian Journal of Transfusion Science |
spelling | doaj-art-f3fa4c1ff56b4c328b85138572e7a0b62025-01-08T09:09:58ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652024-12-0118229630210.4103/ajts.ajts_167_21Syncopal reactions in blood donors: Pathophysiology, clinical course, and featuresAbhishekh BasavarajegowdaY. C. NaliniVasovagal syncope (VVS) in donors is a transient loss of consciousness due to short-term global cerebral hypoperfusion, which has a rapid onset and has complete spontaneous recovery. VVS may be triggered by pain, fear, anxiety, or emotional upset and loss of blood perse. It is an exaggeration of an adaptive response meant to assist in reducing the amount of bleeding/loss of blood. The four major components necessary for rapid cardiovascular adjustments to supine or upright posture, otherwise called orthostasis, are the autonomic nervous system, adequate blood volume, and intact skeletal and respiratory muscle pumps. The taxing of these autoregulatory mechanisms and their inability to compensate sufficiently results in VVS. VVR episodes can be described in 3 phases; Presyncope, Syncope, and Postsyncope. The actual syncope generally lasts for <15 s, comprising staring, muscle jerks, eye deviation/rolling, sometimes incontinence, loss of consciousness, gasping, snoring, apnea, inability to move/react, etc., The postsyncopal phase is the longest, which is generally manifested as fatigue.https://journals.lww.com/10.4103/ajts.ajts_167_21blood donationemotional syncopepathophysiologyvasovagal syncope |
spellingShingle | Abhishekh Basavarajegowda Y. C. Nalini Syncopal reactions in blood donors: Pathophysiology, clinical course, and features Asian Journal of Transfusion Science blood donation emotional syncope pathophysiology vasovagal syncope |
title | Syncopal reactions in blood donors: Pathophysiology, clinical course, and features |
title_full | Syncopal reactions in blood donors: Pathophysiology, clinical course, and features |
title_fullStr | Syncopal reactions in blood donors: Pathophysiology, clinical course, and features |
title_full_unstemmed | Syncopal reactions in blood donors: Pathophysiology, clinical course, and features |
title_short | Syncopal reactions in blood donors: Pathophysiology, clinical course, and features |
title_sort | syncopal reactions in blood donors pathophysiology clinical course and features |
topic | blood donation emotional syncope pathophysiology vasovagal syncope |
url | https://journals.lww.com/10.4103/ajts.ajts_167_21 |
work_keys_str_mv | AT abhishekhbasavarajegowda syncopalreactionsinblooddonorspathophysiologyclinicalcourseandfeatures AT ycnalini syncopalreactionsinblooddonorspathophysiologyclinicalcourseandfeatures |