Relationship between Helicobacter Pylori Gastritis and Plasma Amino Acids
Introduction: This study investigated the relationship between plasma amino acid levels and the presence of Helicobacter pylori (H. pylori) in children. Materials and Methods: The study included 88 pediatric patients with gastritis (30 H. pylori-positive and 58 H. pylori-negative) and a control gro...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2025-08-01
|
| Series: | Güncel Pediatri |
| Subjects: | |
| Online Access: | https://www.guncelpediatri.com/articles/relationship-between-helicobacter-pylori-gastritis-and-plasma-amino-acids/doi/jcp.2025.32767 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849228976041492480 |
|---|---|
| author | Derya Altay Burcu Özşeker Yazman Merve Başol Göksülük Mustafa Kendirci Duran Arslan |
| author_facet | Derya Altay Burcu Özşeker Yazman Merve Başol Göksülük Mustafa Kendirci Duran Arslan |
| author_sort | Derya Altay |
| collection | DOAJ |
| description | Introduction: This study investigated the relationship between plasma amino acid levels and the presence of Helicobacter pylori (H. pylori) in children.
Materials and Methods: The study included 88 pediatric patients with gastritis (30 H. pylori-positive and 58 H. pylori-negative) and a control group of 32 children. Plasma amino acid levels were assessed using liquid chromatography-tandem mass spectrometry, and dietary amino acid intake for all participants was estimated based on a three-day dietary questionnaire.
Results: Plasma glycine, alanine and histidine levels were significantly high in the H. pylori-negative group compared to the other groups (p<0.05). Plasma cysteine, homocysteine and hydroxylysine levels were significantly higher in the control group compared to both gastritis groups (p<0.05). Plasma asparagine, glutamine and histidine levels were found significantly lower in the H. pylori positive group than in the H. pylori negative group (p<0.05).
Conclusion: This study identified a moderate correlation between plasma levels of asparagine, glutamine, and histidine and the presence of H. pylori gastritis in children. |
| format | Article |
| id | doaj-art-f3ebd8cc8eab4f8ebdd1a221d340dbf9 |
| institution | Kabale University |
| issn | 1308-6308 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Güncel Pediatri |
| spelling | doaj-art-f3ebd8cc8eab4f8ebdd1a221d340dbf92025-08-22T12:04:18ZengGalenos Publishing HouseGüncel Pediatri1308-63082025-08-0123210511110.4274/jcp.2025.32767Relationship between Helicobacter Pylori Gastritis and Plasma Amino AcidsDerya Altay0https://orcid.org/0000-0002-7415-1595Burcu Özşeker Yazman1https://orcid.org/0000-0002-7915-8016Merve Başol Göksülük2https://orcid.org/0000-0002-2223-7856Mustafa Kendirci3https://orcid.org/0000-0002-2100-3628Duran Arslan4https://orcid.org/0000-0002-1906-7999Erciyes University Faculty of Medicine, Department of Pediatric Gastroenterology, Kayseri, TürkiyeErciyes University Faculty of Medicine, Department of Pediatric Nutrition and Dietetics, Kayseri, TürkiyeErciyes University Faculty of Medicine, Department of Biostatistics, Kayseri, TürkiyeErciyes University Faculty of Medicine, Department of Pediatric Metabolism, Kayseri, TürkiyeErciyes University Faculty of Medicine, Department of Pediatric Gastroenterology, Kayseri, TürkiyeIntroduction: This study investigated the relationship between plasma amino acid levels and the presence of Helicobacter pylori (H. pylori) in children. Materials and Methods: The study included 88 pediatric patients with gastritis (30 H. pylori-positive and 58 H. pylori-negative) and a control group of 32 children. Plasma amino acid levels were assessed using liquid chromatography-tandem mass spectrometry, and dietary amino acid intake for all participants was estimated based on a three-day dietary questionnaire. Results: Plasma glycine, alanine and histidine levels were significantly high in the H. pylori-negative group compared to the other groups (p<0.05). Plasma cysteine, homocysteine and hydroxylysine levels were significantly higher in the control group compared to both gastritis groups (p<0.05). Plasma asparagine, glutamine and histidine levels were found significantly lower in the H. pylori positive group than in the H. pylori negative group (p<0.05). Conclusion: This study identified a moderate correlation between plasma levels of asparagine, glutamine, and histidine and the presence of H. pylori gastritis in children.https://www.guncelpediatri.com/articles/relationship-between-helicobacter-pylori-gastritis-and-plasma-amino-acids/doi/jcp.2025.32767helicobacter pyloriplasma amino acidsgastritispediatric |
| spellingShingle | Derya Altay Burcu Özşeker Yazman Merve Başol Göksülük Mustafa Kendirci Duran Arslan Relationship between Helicobacter Pylori Gastritis and Plasma Amino Acids Güncel Pediatri helicobacter pylori plasma amino acids gastritis pediatric |
| title | Relationship between Helicobacter Pylori Gastritis and Plasma Amino Acids |
| title_full | Relationship between Helicobacter Pylori Gastritis and Plasma Amino Acids |
| title_fullStr | Relationship between Helicobacter Pylori Gastritis and Plasma Amino Acids |
| title_full_unstemmed | Relationship between Helicobacter Pylori Gastritis and Plasma Amino Acids |
| title_short | Relationship between Helicobacter Pylori Gastritis and Plasma Amino Acids |
| title_sort | relationship between helicobacter pylori gastritis and plasma amino acids |
| topic | helicobacter pylori plasma amino acids gastritis pediatric |
| url | https://www.guncelpediatri.com/articles/relationship-between-helicobacter-pylori-gastritis-and-plasma-amino-acids/doi/jcp.2025.32767 |
| work_keys_str_mv | AT deryaaltay relationshipbetweenhelicobacterpylorigastritisandplasmaaminoacids AT burcuozsekeryazman relationshipbetweenhelicobacterpylorigastritisandplasmaaminoacids AT mervebasolgoksuluk relationshipbetweenhelicobacterpylorigastritisandplasmaaminoacids AT mustafakendirci relationshipbetweenhelicobacterpylorigastritisandplasmaaminoacids AT duranarslan relationshipbetweenhelicobacterpylorigastritisandplasmaaminoacids |