Evaluation of tramadol/paracetamol 75 mg/650 mg combination therapy for early-stage knee osteoarthritis: a retrospective observational study

Evaluation of tramadol/paracetamol 75 mg/650 mg combination therapy for early-stage knee osteoarthritis: a retrospective observational study

Objective. Knee osteoarthritis (KOA) is a progressive joint disorder that significantly impairs patients’ quality of life. Effective long-term management of KOA remains challenging due to limited pharmacological options and associated adverse effects. This monocentric, retrospective observational s...

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Main Authors: Alessandro Conforti, Cosimo Ruggiero, Nastasja Palombi, Filippo Messina, Marco Bonifacio, Linda Lucchetti, Marco Ruggiero, Giuseppe La Cava, Roberto Piazza, Mario Mangrella
Format: Article
Language:English
Published: PAGEPress Publications 2025-07-01
Series:Reumatismo
Subjects:
Knee osteoarthritis
tramadol/paracetamol
numerical rating scale
WOMAC Osteoarthritis Index
Pittsburgh Sleep Quality Index
Online Access:https://www.reumatismo.org/reuma/article/view/1872
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https://www.reumatismo.org/reuma/article/view/1872

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