Mycophenolic Acid Inhibits Replication of Type 2 Winnipeg, a Cerebrospinal Fluid-Derived Reovirus Isolate
BACKGROUND: The role of reoviruses in human disease is uncertain. Most identified cases are sporadic and asymptomatic or produce minor upper respiratory or gastrointestinal symptoms. In November 1997, a reovirus was isolated from the cerebrospinal fluid of a severe combined immune deficient infant i...
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| Format: | Article |
| Language: | English |
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Wiley
2004-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2004/387272 |
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| _version_ | 1841524427107336192 |
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| author | Laura L Hermann Kevin M Coombs |
| author_facet | Laura L Hermann Kevin M Coombs |
| author_sort | Laura L Hermann |
| collection | DOAJ |
| description | BACKGROUND: The role of reoviruses in human disease is uncertain. Most identified cases are sporadic and asymptomatic or produce minor upper respiratory or gastrointestinal symptoms. In November 1997, a reovirus was isolated from the cerebrospinal fluid of a severe combined immune deficient infant in Winnipeg, Manitoba. RNA characterization and sequencing studies demonstrated this reovirus isolate to be unique. Thus, the virus was named Type 2 Winnipeg (T2W). |
| format | Article |
| id | doaj-art-f3c25bcd12e8440094499d0952d9bab3 |
| institution | Kabale University |
| issn | 1712-9532 |
| language | English |
| publishDate | 2004-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-f3c25bcd12e8440094499d0952d9bab32025-02-03T05:53:16ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322004-01-0115526126510.1155/2004/387272Mycophenolic Acid Inhibits Replication of Type 2 Winnipeg, a Cerebrospinal Fluid-Derived Reovirus IsolateLaura L Hermann0Kevin M Coombs1Departments of Medical Microbiology and Infectious Diseases, and Physiology, University of Manitoba, Winnipeg, Manitoba, CanadaDepartments of Medical Microbiology and Infectious Diseases, and Physiology, University of Manitoba, Winnipeg, Manitoba, CanadaBACKGROUND: The role of reoviruses in human disease is uncertain. Most identified cases are sporadic and asymptomatic or produce minor upper respiratory or gastrointestinal symptoms. In November 1997, a reovirus was isolated from the cerebrospinal fluid of a severe combined immune deficient infant in Winnipeg, Manitoba. RNA characterization and sequencing studies demonstrated this reovirus isolate to be unique. Thus, the virus was named Type 2 Winnipeg (T2W).http://dx.doi.org/10.1155/2004/387272 |
| spellingShingle | Laura L Hermann Kevin M Coombs Mycophenolic Acid Inhibits Replication of Type 2 Winnipeg, a Cerebrospinal Fluid-Derived Reovirus Isolate Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Mycophenolic Acid Inhibits Replication of Type 2 Winnipeg, a Cerebrospinal Fluid-Derived Reovirus Isolate |
| title_full | Mycophenolic Acid Inhibits Replication of Type 2 Winnipeg, a Cerebrospinal Fluid-Derived Reovirus Isolate |
| title_fullStr | Mycophenolic Acid Inhibits Replication of Type 2 Winnipeg, a Cerebrospinal Fluid-Derived Reovirus Isolate |
| title_full_unstemmed | Mycophenolic Acid Inhibits Replication of Type 2 Winnipeg, a Cerebrospinal Fluid-Derived Reovirus Isolate |
| title_short | Mycophenolic Acid Inhibits Replication of Type 2 Winnipeg, a Cerebrospinal Fluid-Derived Reovirus Isolate |
| title_sort | mycophenolic acid inhibits replication of type 2 winnipeg a cerebrospinal fluid derived reovirus isolate |
| url | http://dx.doi.org/10.1155/2004/387272 |
| work_keys_str_mv | AT lauralhermann mycophenolicacidinhibitsreplicationoftype2winnipegacerebrospinalfluidderivedreovirusisolate AT kevinmcoombs mycophenolicacidinhibitsreplicationoftype2winnipegacerebrospinalfluidderivedreovirusisolate |