Selective identification of polyploid hepatocellular carcinomas with poor prognosis by artificial intelligence-based pathological image recognition

Abstract Background Polyploidy is frequently observed in cancer cells and is closely associated with chromosomal instability, which can lead to cancer progression. Polyploid cancers are more aggressive than diploid cancers, and polyploidy has been shown to be a prognostic marker for hepatocellular c...

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Main Authors: Takanori Matsuura, Masatoshi Abe, Yoshiyuki Harada, Masahiro Kido, Hajime Nagahara, Yuzo Kodama, Yoshihide Ueda, Eiji Hara, Hirohiko Niioka, Tomonori Matsumoto
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00967-8
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