Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock

Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock

The circadian clock enables organisms to synchronize biochemical and physiological processes over a 24 hr period. Natural changes in lighting conditions, as well as artificial disruptions like jet lag or shift work, can advance or delay the clock phase to align physiology with the environment. Withi...

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Bibliographic Details
Main Authors: Andrea Brenna, Micaela Borsa, Gabriella Saro, Jürgen A Ripperger, Dominique A Glauser, Zhihong Yang, Antoine Adamantidis, Urs Albrecht
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-02-01
Series:eLife
Subjects:
light adaptation
environmental signal
clock genes
kinases
jet lag
shift work
Online Access:https://elifesciences.org/articles/97029
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