Outcome of Coronary Edge In-stent Restenosis Management by Restenting Versus Drug-Eluting Balloon

Background: The optimal therapeutic strategy for coronary intervention in edge in-stent restenosis (edge ISR) remains less well-defined. Aim: The aim of this study was to assess 12-month outcomes of re-stenting using drug-eluting stents (DESs) versus using drug-eluting balloon (DEB) for managing cor...

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Main Authors: Yasser Gaber Metwally, Khaled Yehia Elnady, Tarek Abd El-Ghaffar, Eman Hesham Seddik, Ahmed Shaker, Fathy Mohamed Swailem
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Journal of Indian College of Cardiology
Subjects:
Online Access:https://journals.lww.com/10.4103/jicc.jicc_36_24
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author Yasser Gaber Metwally
Khaled Yehia Elnady
Tarek Abd El-Ghaffar
Eman Hesham Seddik
Ahmed Shaker
Fathy Mohamed Swailem
author_facet Yasser Gaber Metwally
Khaled Yehia Elnady
Tarek Abd El-Ghaffar
Eman Hesham Seddik
Ahmed Shaker
Fathy Mohamed Swailem
author_sort Yasser Gaber Metwally
collection DOAJ
description Background: The optimal therapeutic strategy for coronary intervention in edge in-stent restenosis (edge ISR) remains less well-defined. Aim: The aim of this study was to assess 12-month outcomes of re-stenting using drug-eluting stents (DESs) versus using drug-eluting balloon (DEB) for managing coronary edge ISR. Patients and Methods: One hundred and four patients with edge ISR were randomly assigned to either DES or DEB. The primary endpoint was stent failure at 12-month follow-up. Results: Significantly lower target vessel revascularization among the DEB group compared to restenting group, (7.7% vs. 23.1%, P = 0.04). Likewise, target vessel-related myocardial infarction rate was significantly lower among the DEB group than restenting (5.7% vs. 23.1%, P = 0.04). On the other hand, there were no significant differences in the rates of deaths or restenosis between the two groups. Conclusion: The DEB is superior to the DES with better both safety and efficacy.
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institution Kabale University
issn 1561-8811
2213-3615
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Indian College of Cardiology
spelling doaj-art-f36d46cb66ab4be3882f9216b9f44ffc2025-01-12T10:26:24ZengWolters Kluwer Medknow PublicationsJournal of Indian College of Cardiology1561-88112213-36152024-12-0114411411810.4103/jicc.jicc_36_24Outcome of Coronary Edge In-stent Restenosis Management by Restenting Versus Drug-Eluting BalloonYasser Gaber MetwallyKhaled Yehia ElnadyTarek Abd El-GhaffarEman Hesham SeddikAhmed ShakerFathy Mohamed SwailemBackground: The optimal therapeutic strategy for coronary intervention in edge in-stent restenosis (edge ISR) remains less well-defined. Aim: The aim of this study was to assess 12-month outcomes of re-stenting using drug-eluting stents (DESs) versus using drug-eluting balloon (DEB) for managing coronary edge ISR. Patients and Methods: One hundred and four patients with edge ISR were randomly assigned to either DES or DEB. The primary endpoint was stent failure at 12-month follow-up. Results: Significantly lower target vessel revascularization among the DEB group compared to restenting group, (7.7% vs. 23.1%, P = 0.04). Likewise, target vessel-related myocardial infarction rate was significantly lower among the DEB group than restenting (5.7% vs. 23.1%, P = 0.04). On the other hand, there were no significant differences in the rates of deaths or restenosis between the two groups. Conclusion: The DEB is superior to the DES with better both safety and efficacy.https://journals.lww.com/10.4103/jicc.jicc_36_24coronary edgeeluting ballooneluting stentstent restenosis
spellingShingle Yasser Gaber Metwally
Khaled Yehia Elnady
Tarek Abd El-Ghaffar
Eman Hesham Seddik
Ahmed Shaker
Fathy Mohamed Swailem
Outcome of Coronary Edge In-stent Restenosis Management by Restenting Versus Drug-Eluting Balloon
Journal of Indian College of Cardiology
coronary edge
eluting balloon
eluting stent
stent restenosis
title Outcome of Coronary Edge In-stent Restenosis Management by Restenting Versus Drug-Eluting Balloon
title_full Outcome of Coronary Edge In-stent Restenosis Management by Restenting Versus Drug-Eluting Balloon
title_fullStr Outcome of Coronary Edge In-stent Restenosis Management by Restenting Versus Drug-Eluting Balloon
title_full_unstemmed Outcome of Coronary Edge In-stent Restenosis Management by Restenting Versus Drug-Eluting Balloon
title_short Outcome of Coronary Edge In-stent Restenosis Management by Restenting Versus Drug-Eluting Balloon
title_sort outcome of coronary edge in stent restenosis management by restenting versus drug eluting balloon
topic coronary edge
eluting balloon
eluting stent
stent restenosis
url https://journals.lww.com/10.4103/jicc.jicc_36_24
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AT tarekabdelghaffar outcomeofcoronaryedgeinstentrestenosismanagementbyrestentingversusdrugelutingballoon
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