Characteristics, treatments and outcomes in patients with severe burn wounds; a 10 year cohort study on acute and reconstructive treatment.

Reports on treatment characteristics and long term outcomes for severe burns are scarce, while the need to compare outcomes of novel treatment modalities to standard of care is increasing. Our national database on burn treatment enabled analysis of patient as well as treatment characteristics during...

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Main Authors: Lucindi Smit, Anouk Pijpe, Cindy Nguyen, Tara Hartsuiker, Matthea Stoop, Anouk van Heel, Eelke Bosma, Cornelis H van der Vlies, Paul P M van Zuijlen, Margriet E van Baar, Esther Middelkoop, Dutch Burn Repository group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0313287
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author Lucindi Smit
Anouk Pijpe
Cindy Nguyen
Tara Hartsuiker
Matthea Stoop
Anouk van Heel
Eelke Bosma
Cornelis H van der Vlies
Paul P M van Zuijlen
Margriet E van Baar
Esther Middelkoop
Dutch Burn Repository group
author_facet Lucindi Smit
Anouk Pijpe
Cindy Nguyen
Tara Hartsuiker
Matthea Stoop
Anouk van Heel
Eelke Bosma
Cornelis H van der Vlies
Paul P M van Zuijlen
Margriet E van Baar
Esther Middelkoop
Dutch Burn Repository group
author_sort Lucindi Smit
collection DOAJ
description Reports on treatment characteristics and long term outcomes for severe burns are scarce, while the need to compare outcomes of novel treatment modalities to standard of care is increasing. Our national database on burn treatment enabled analysis of patient as well as treatment characteristics during acute treatment and following reconstructive procedures. Furthermore, outcome data of longitudinal scar assessments were analysed from a single burn centre database. Acute and reconstructive data were analysed for patients admitted to the three Dutch burn centres with total body surface area burned of ≥ 20% TBSA. Long term outcome was analysed from a single centre scar database, both for a period of 2009-2019. Treatment characteristics from 396 surviving acute burn patients were analysed. Surgical treatment was required in 89.6% of these patients and 110 patients (27.8%) needed reconstructive surgery in the years after the burn incident, with a mean of 4.4 reconstructive procedures per patient. Main indications were contractures (70.5%) and arms (45.0%) and head and neck region (41.2%) were most frequently affected. Techniques used for reconstructive corrections were predominantly excision, release and flaps (54.7%), followed by skin transplants (32.4%). Scar quality was significantly worse in patients with more severe burns compared to those with TBSA < 20% during prolonged times. These data provide insight into health care utilization, treatment characteristics and outcomes in severely burned patients. These real-world data can guide future development of improved treatment strategies for at risk patients as well as anatomical locations.
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spelling doaj-art-f35d2a25192648f3ad37209b8cfb3bf92024-11-25T05:31:14ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-011911e031328710.1371/journal.pone.0313287Characteristics, treatments and outcomes in patients with severe burn wounds; a 10 year cohort study on acute and reconstructive treatment.Lucindi SmitAnouk PijpeCindy NguyenTara HartsuikerMatthea StoopAnouk van HeelEelke BosmaCornelis H van der VliesPaul P M van ZuijlenMargriet E van BaarEsther MiddelkoopDutch Burn Repository groupReports on treatment characteristics and long term outcomes for severe burns are scarce, while the need to compare outcomes of novel treatment modalities to standard of care is increasing. Our national database on burn treatment enabled analysis of patient as well as treatment characteristics during acute treatment and following reconstructive procedures. Furthermore, outcome data of longitudinal scar assessments were analysed from a single burn centre database. Acute and reconstructive data were analysed for patients admitted to the three Dutch burn centres with total body surface area burned of ≥ 20% TBSA. Long term outcome was analysed from a single centre scar database, both for a period of 2009-2019. Treatment characteristics from 396 surviving acute burn patients were analysed. Surgical treatment was required in 89.6% of these patients and 110 patients (27.8%) needed reconstructive surgery in the years after the burn incident, with a mean of 4.4 reconstructive procedures per patient. Main indications were contractures (70.5%) and arms (45.0%) and head and neck region (41.2%) were most frequently affected. Techniques used for reconstructive corrections were predominantly excision, release and flaps (54.7%), followed by skin transplants (32.4%). Scar quality was significantly worse in patients with more severe burns compared to those with TBSA < 20% during prolonged times. These data provide insight into health care utilization, treatment characteristics and outcomes in severely burned patients. These real-world data can guide future development of improved treatment strategies for at risk patients as well as anatomical locations.https://doi.org/10.1371/journal.pone.0313287
spellingShingle Lucindi Smit
Anouk Pijpe
Cindy Nguyen
Tara Hartsuiker
Matthea Stoop
Anouk van Heel
Eelke Bosma
Cornelis H van der Vlies
Paul P M van Zuijlen
Margriet E van Baar
Esther Middelkoop
Dutch Burn Repository group
Characteristics, treatments and outcomes in patients with severe burn wounds; a 10 year cohort study on acute and reconstructive treatment.
PLoS ONE
title Characteristics, treatments and outcomes in patients with severe burn wounds; a 10 year cohort study on acute and reconstructive treatment.
title_full Characteristics, treatments and outcomes in patients with severe burn wounds; a 10 year cohort study on acute and reconstructive treatment.
title_fullStr Characteristics, treatments and outcomes in patients with severe burn wounds; a 10 year cohort study on acute and reconstructive treatment.
title_full_unstemmed Characteristics, treatments and outcomes in patients with severe burn wounds; a 10 year cohort study on acute and reconstructive treatment.
title_short Characteristics, treatments and outcomes in patients with severe burn wounds; a 10 year cohort study on acute and reconstructive treatment.
title_sort characteristics treatments and outcomes in patients with severe burn wounds a 10 year cohort study on acute and reconstructive treatment
url https://doi.org/10.1371/journal.pone.0313287
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