From Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected Diagnosis

Tuberculosis (TB) of the rib is an uncommon manifestation of extrapulmonary TB that can pose significant diagnostic challenges, especially when presenting as a breast mass. We report the case of a 74-year-old woman who presented with a left breast lump, initially suspected to be a plasmacytoma due t...

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Main Authors: Hafedh Abbassi, Badra Bannour, Sarra Yacoub, Ekram Guerbej, Imen Bannour, Samir Hidar, Moncef Mokni
Format: Article
Language:English
Published: Galenos Publishing House 2025-01-01
Series:European Journal of Breast Health
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Online Access:https://www.eurjbreasthealth.com/articles/from-plasmacytoma-to-rib-tuberculosis-the-case-of-a-breast-mass-with-an-unexpected-diagnosis/doi/ejbh.galenos.2024.2024-10-6
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author Hafedh Abbassi
Badra Bannour
Sarra Yacoub
Ekram Guerbej
Imen Bannour
Samir Hidar
Moncef Mokni
author_facet Hafedh Abbassi
Badra Bannour
Sarra Yacoub
Ekram Guerbej
Imen Bannour
Samir Hidar
Moncef Mokni
author_sort Hafedh Abbassi
collection DOAJ
description Tuberculosis (TB) of the rib is an uncommon manifestation of extrapulmonary TB that can pose significant diagnostic challenges, especially when presenting as a breast mass. We report the case of a 74-year-old woman who presented with a left breast lump, initially suspected to be a plasmacytoma due to its imaging characteristics and clinical history. The mass was surgically excised, and histopathological analysis revealed granulomatous inflammation with caseous necrosis, suggesting TB. TB-polymerase chain reaction confirmed the diagnosis, despite negative Ziehl-Neelsen staining. The patient was treated with anti-tubercular therapy for twelve months, resulting in a favorable clinical outcome. This case highlights the importance of considering rib TB in the differential diagnosis of breast masses, particularly in endemic areas, and underscores the role of comprehensive diagnostic evaluations for timely and effective treatment.
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institution Kabale University
issn 2587-0831
language English
publishDate 2025-01-01
publisher Galenos Publishing House
record_format Article
series European Journal of Breast Health
spelling doaj-art-f33d75aa46f9478eace50c5b048779b82025-01-07T11:09:32ZengGalenos Publishing HouseEuropean Journal of Breast Health2587-08312025-01-01211858910.4274/ejbh.galenos.2024.2024-10-6From Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected DiagnosisHafedh Abbassi0https://orcid.org/0000-0002-3547-1297Badra Bannour1https://orcid.org/0000-0003-3126-2233Sarra Yacoub2https://orcid.org/0009-0008-1987-6121Ekram Guerbej3https://orcid.org/0009-0007-2192-2476Imen Bannour4https://orcid.org/0009-0009-4497-6172Samir Hidar5https://orcid.org/0000-0002-1267-3451Moncef Mokni6https://orcid.org/0000-0002-1357-9870Department of Obstetrics and Gynecology, University of Sousse Faculty of Medicine of Sousse, Farhat Hached Teaching Hospital, Sousse, TunisiaDepartment of Obstetrics and Gynecology, University of Sousse Faculty of Medicine of Sousse, Farhat Hached Teaching Hospital, Sousse, TunisiaDepartment of Pathology, University of Sousse Faculty of Medicine of Sousse, Farhat Hached Teaching Hospital, Sousse, TunisiaDepartment of Obstetrics and Gynecology, University of Sousse Faculty of Medicine of Sousse, Farhat Hached Teaching Hospital, Sousse, TunisiaDepartment of Obstetrics and Gynecology, University of Sousse Faculty of Medicine of Sousse, Farhat Hached Teaching Hospital, Sousse, TunisiaDepartment of Obstetrics and Gynecology, University of Sousse Faculty of Medicine of Sousse, Farhat Hached Teaching Hospital, Sousse, TunisiaDepartment of Pathology, University of Sousse Faculty of Medicine of Sousse, Farhat Hached Teaching Hospital, Sousse, TunisiaTuberculosis (TB) of the rib is an uncommon manifestation of extrapulmonary TB that can pose significant diagnostic challenges, especially when presenting as a breast mass. We report the case of a 74-year-old woman who presented with a left breast lump, initially suspected to be a plasmacytoma due to its imaging characteristics and clinical history. The mass was surgically excised, and histopathological analysis revealed granulomatous inflammation with caseous necrosis, suggesting TB. TB-polymerase chain reaction confirmed the diagnosis, despite negative Ziehl-Neelsen staining. The patient was treated with anti-tubercular therapy for twelve months, resulting in a favorable clinical outcome. This case highlights the importance of considering rib TB in the differential diagnosis of breast masses, particularly in endemic areas, and underscores the role of comprehensive diagnostic evaluations for timely and effective treatment.https://www.eurjbreasthealth.com/articles/from-plasmacytoma-to-rib-tuberculosis-the-case-of-a-breast-mass-with-an-unexpected-diagnosis/doi/ejbh.galenos.2024.2024-10-6breast diseaseplasmocytomasurgerytuberculosis
spellingShingle Hafedh Abbassi
Badra Bannour
Sarra Yacoub
Ekram Guerbej
Imen Bannour
Samir Hidar
Moncef Mokni
From Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected Diagnosis
European Journal of Breast Health
breast disease
plasmocytoma
surgery
tuberculosis
title From Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected Diagnosis
title_full From Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected Diagnosis
title_fullStr From Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected Diagnosis
title_full_unstemmed From Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected Diagnosis
title_short From Plasmacytoma to Rib Tuberculosis: The Case of A Breast Mass With An Unexpected Diagnosis
title_sort from plasmacytoma to rib tuberculosis the case of a breast mass with an unexpected diagnosis
topic breast disease
plasmocytoma
surgery
tuberculosis
url https://www.eurjbreasthealth.com/articles/from-plasmacytoma-to-rib-tuberculosis-the-case-of-a-breast-mass-with-an-unexpected-diagnosis/doi/ejbh.galenos.2024.2024-10-6
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