Herpes simplex virus-induced upregulation of inflammatory cytokines in human gingival fibroblasts

Herpes simplex virus-induced upregulation of inflammatory cytokines in human gingival fibroblasts

Abstract Herpes simplex virus type 1 (HSV-1) is the leading pathogen in the maxillo-facial region, affecting millions of individuals worldwide. Its periodic reactivation aligns with the most common course pattern of periodontal disease. The present study used RNA sequencing to investigate the transc...

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Bibliographic Details
Main Authors: Yu Zhang, Kalam Lo, Chunmei Wang, Guoliang Zhou, Xiping Feng, Jing Ni, Xi Chen
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Virology Journal
Subjects:
Herpes simplex virus
Human gingival fibroblasts
Transcriptome
Periodontitis
Online Access:https://doi.org/10.1186/s12985-024-02595-5
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