Case Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus
Congenital diarrhea and enteropathies (CODEs) are a rare heterogeneous group of inherited disorders that typically present with severe chronic diarrhea during the first weeks of life. As a broad range of illnesses can present similarly in infants, establishing a definitive cause for CODEs is challen...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2024.1494599/full |
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| author | Cuifang Zheng Song Sun Ying Gong Shijian Miao Kuiran Dong Ying Huang |
| author_facet | Cuifang Zheng Song Sun Ying Gong Shijian Miao Kuiran Dong Ying Huang |
| author_sort | Cuifang Zheng |
| collection | DOAJ |
| description | Congenital diarrhea and enteropathies (CODEs) are a rare heterogeneous group of inherited disorders that typically present with severe chronic diarrhea during the first weeks of life. As a broad range of illnesses can present similarly in infants, establishing a definitive cause for CODEs is challenging. In this report, two infants were suspected to have CODE, with neonatal-onset chronic diarrhea and protein-losing enteropathy finally found to be due to intestinal malrotation and chronic midgut volvulus. Although the disease onset time was during the neonatal period, the typical findings of intestinal malrotation and volvulus were not present. Following the diagnostic approach for CODEs, both patients underwent extensive examinations without a definitive diagnosis. Intestinal malrotation was incidentally detected by an abdominal CT examination. After surgical correction of the underlying malrotation (Ladd's procedure), both infants had resolution of their diarrhea and hypoalbuminemia. |
| format | Article |
| id | doaj-art-f301603f21e041babb69224ee531e156 |
| institution | Kabale University |
| issn | 2296-2360 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj-art-f301603f21e041babb69224ee531e1562025-01-14T06:10:30ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-01-011210.3389/fped.2024.14945991494599Case Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulusCuifang ZhengSong SunYing GongShijian MiaoKuiran DongYing HuangCongenital diarrhea and enteropathies (CODEs) are a rare heterogeneous group of inherited disorders that typically present with severe chronic diarrhea during the first weeks of life. As a broad range of illnesses can present similarly in infants, establishing a definitive cause for CODEs is challenging. In this report, two infants were suspected to have CODE, with neonatal-onset chronic diarrhea and protein-losing enteropathy finally found to be due to intestinal malrotation and chronic midgut volvulus. Although the disease onset time was during the neonatal period, the typical findings of intestinal malrotation and volvulus were not present. Following the diagnostic approach for CODEs, both patients underwent extensive examinations without a definitive diagnosis. Intestinal malrotation was incidentally detected by an abdominal CT examination. After surgical correction of the underlying malrotation (Ladd's procedure), both infants had resolution of their diarrhea and hypoalbuminemia.https://www.frontiersin.org/articles/10.3389/fped.2024.1494599/fullchronic diarrheaintestinal malrotationvolvuluscongenital diarrhea and enteropathiesprotein-losing enteropathymalabsorption syndrome |
| spellingShingle | Cuifang Zheng Song Sun Ying Gong Shijian Miao Kuiran Dong Ying Huang Case Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus Frontiers in Pediatrics chronic diarrhea intestinal malrotation volvulus congenital diarrhea and enteropathies protein-losing enteropathy malabsorption syndrome |
| title | Case Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus |
| title_full | Case Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus |
| title_fullStr | Case Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus |
| title_full_unstemmed | Case Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus |
| title_short | Case Report: Neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus |
| title_sort | case report neonatal onset intractable diarrhea and hypoproteinemia due to intestinal malrotation and chronic midgut volvulus |
| topic | chronic diarrhea intestinal malrotation volvulus congenital diarrhea and enteropathies protein-losing enteropathy malabsorption syndrome |
| url | https://www.frontiersin.org/articles/10.3389/fped.2024.1494599/full |
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