First Tunisian cluster admissions of critically ill patients with multisystem inflammatory syndrome in children (MIS-C)
Background: Multisystem inflammatory syndrome in children (MIS-C) is a new serious emerging disease that is temporally related to previous exposure to coronavirus infection disease (COVID-19). Aim: To describe the clinical features, laboratory findings, therapies and outcomes for the first Tuni...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2021-02-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Online Access: | https://www.mjhid.org/index.php/mjhid/article/view/4523 |
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| author | aida borgi |
| author_facet | aida borgi |
| author_sort | aida borgi |
| collection | DOAJ |
| description | Background: Multisystem inflammatory syndrome in children (MIS-C) is a new serious emerging disease that is temporally related to previous exposure to coronavirus infection disease (COVID-19).
Aim: To describe the clinical features, laboratory findings, therapies and outcomes for the first Tunisian cluster admissions of critically ill children with severe MIS-C.
Methods: Retrospective study conducted between 01 November and 30 November 2020
We included 8 children aged less than 15 years who were admitted to our pediatric intensive care and met the criteria for MIS-C according to the WHO definition case. We reviewed the medical records of all patients to collect demographic and clinical data, severity scores, laboratory test results, echocardiographic findings, treatment, and outcomes.
Results: All children were previously fit and well. Seven patients were boys. Known exposure to COVID-19 was reported in 4 cases. Fever and gastrointestinal symptoms were reported in all cases. Five patients had marked abdominal pain and were examined by the surgeon for a possible appendicitis. Seven patients had diarrhea. On examination, we found a rash (n=7), a conjunctivitis (n=7), a cheilitis (n=5) and a meningism (n=3). We reported cardiac dysfunction in 7 cases and a shock with hypotension in 3 cases. All patients received immunoglobulins, methyl prednisolone and a low dose of aspirine. No deaths occurred.
Conclusion: We reported here the first Tunisian cluster admissions of 8 critically ill children with MIS-C to highlight the increase of a new severe emerging disease with an evidence of prior COVID-19 infection in older children. |
| format | Article |
| id | doaj-art-f2e1a063f40c489cb9729e14e62407dc |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2021-02-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-f2e1a063f40c489cb9729e14e62407dc2025-01-02T10:51:11ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062021-02-0113110.4084/mjhid.2021.023First Tunisian cluster admissions of critically ill patients with multisystem inflammatory syndrome in children (MIS-C)aida borgi0PICU- Children’s Hospital of TunisBackground: Multisystem inflammatory syndrome in children (MIS-C) is a new serious emerging disease that is temporally related to previous exposure to coronavirus infection disease (COVID-19). Aim: To describe the clinical features, laboratory findings, therapies and outcomes for the first Tunisian cluster admissions of critically ill children with severe MIS-C. Methods: Retrospective study conducted between 01 November and 30 November 2020 We included 8 children aged less than 15 years who were admitted to our pediatric intensive care and met the criteria for MIS-C according to the WHO definition case. We reviewed the medical records of all patients to collect demographic and clinical data, severity scores, laboratory test results, echocardiographic findings, treatment, and outcomes. Results: All children were previously fit and well. Seven patients were boys. Known exposure to COVID-19 was reported in 4 cases. Fever and gastrointestinal symptoms were reported in all cases. Five patients had marked abdominal pain and were examined by the surgeon for a possible appendicitis. Seven patients had diarrhea. On examination, we found a rash (n=7), a conjunctivitis (n=7), a cheilitis (n=5) and a meningism (n=3). We reported cardiac dysfunction in 7 cases and a shock with hypotension in 3 cases. All patients received immunoglobulins, methyl prednisolone and a low dose of aspirine. No deaths occurred. Conclusion: We reported here the first Tunisian cluster admissions of 8 critically ill children with MIS-C to highlight the increase of a new severe emerging disease with an evidence of prior COVID-19 infection in older children.https://www.mjhid.org/index.php/mjhid/article/view/4523 |
| spellingShingle | aida borgi First Tunisian cluster admissions of critically ill patients with multisystem inflammatory syndrome in children (MIS-C) Mediterranean Journal of Hematology and Infectious Diseases |
| title | First Tunisian cluster admissions of critically ill patients with multisystem inflammatory syndrome in children (MIS-C) |
| title_full | First Tunisian cluster admissions of critically ill patients with multisystem inflammatory syndrome in children (MIS-C) |
| title_fullStr | First Tunisian cluster admissions of critically ill patients with multisystem inflammatory syndrome in children (MIS-C) |
| title_full_unstemmed | First Tunisian cluster admissions of critically ill patients with multisystem inflammatory syndrome in children (MIS-C) |
| title_short | First Tunisian cluster admissions of critically ill patients with multisystem inflammatory syndrome in children (MIS-C) |
| title_sort | first tunisian cluster admissions of critically ill patients with multisystem inflammatory syndrome in children mis c |
| url | https://www.mjhid.org/index.php/mjhid/article/view/4523 |
| work_keys_str_mv | AT aidaborgi firsttunisianclusteradmissionsofcriticallyillpatientswithmultisysteminflammatorysyndromeinchildrenmisc |