Influence of aging on dermal elastin fiber architecture and skin firmness assessed by finite element modeling

Abstract Skin firmness and elasticity are largely determined by the dermal extracellular matrix, particularly the elastin fiber network. Age-related degradation of elastin alters its architecture, contributing to diminished skin resilience. However, the quantitative relationship between elastin fibe...

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Bibliographic Details
Main Authors: Fei Jiang, Takeshi Tohgasaki, Mayuko Kami, Ryota Sanuki, Yuya Nakata, Shinya Kondo, Xian Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-14393-2
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