Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia

Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia

Cancer is characterized by a remarkable intertumoral, intratumoral, and cellular heterogeneity that might be explained by the cancer stem cell (CSC) and/or the clonal evolution models. CSCs have the ability to generate all different cells of a tumor and to reinitiate the disease after remission. In...

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Bibliographic Details
Main Authors: Fabian Lang, Bartosch Wojcik, Michael A. Rieger
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2015/137164
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