Genome editing in future crop protection: utilizing CRISPR/Cas9 to improve crop resistance against diseases, pests, and weeds

Abstract Increasing population and climate change pose significant threats to global food security by imposing stresses on plants, making them more susceptible to diseases and productivity losses caused by pathogens, pests, and weeds. Traditional breeding strategies are insufficient for rapid develo...

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Main Authors: Ahmad Faizal, Syarul Nugroho, Anca Awal Sembada, Yohanes Theda, Tinta Komariyah, Rizkita Rachmi Esyanti
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Discover Agriculture
Subjects:
Online Access:https://doi.org/10.1007/s44279-024-00124-0
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author Ahmad Faizal
Syarul Nugroho
Anca Awal Sembada
Yohanes Theda
Tinta Komariyah
Rizkita Rachmi Esyanti
author_facet Ahmad Faizal
Syarul Nugroho
Anca Awal Sembada
Yohanes Theda
Tinta Komariyah
Rizkita Rachmi Esyanti
author_sort Ahmad Faizal
collection DOAJ
description Abstract Increasing population and climate change pose significant threats to global food security by imposing stresses on plants, making them more susceptible to diseases and productivity losses caused by pathogens, pests, and weeds. Traditional breeding strategies are insufficient for rapid development of new plant traits that can outpace this productivity downtrend. Modern advances in genome editing technologies, particularly CRISPR/Cas9, have revolutionised crop protection through precise and targeted genome modifications. This allows for the development of resilient crops with enhanced resistance against pathogens, pests, and weeds. This review explores various approaches with which CRISPR/Cas9 is applied for crop protection: knocking out of susceptibility genes, introduction of resistance genes, and modulation of defence genes. Potential applications of CRISPR/Cas9 in crop protection include the introduction of genes conferring resistance to pathogens, disruption of insect genes responsible for survival and reproduction and engineering of herbicide-resistant crops. In conclusion, CRISPR/Cas9 holds great promises in advancing crop protection and thus ensuring food security amidst environmental and population pressures. This review highlights the transformative potential of genome editing in crop protection and calls for continued research and development in this field.
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institution Kabale University
issn 2731-9598
language English
publishDate 2024-11-01
publisher Springer
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series Discover Agriculture
spelling doaj-art-f2a9c294807b40b8a282c1946facbcf32024-11-24T12:39:52ZengSpringerDiscover Agriculture2731-95982024-11-012111710.1007/s44279-024-00124-0Genome editing in future crop protection: utilizing CRISPR/Cas9 to improve crop resistance against diseases, pests, and weedsAhmad Faizal0Syarul Nugroho1Anca Awal Sembada2Yohanes Theda3Tinta Komariyah4Rizkita Rachmi Esyanti5Plant Science and Biotechnology Research Group, School of Life Sciences and Technology, Bandung Institute of TechnologyPlant Breeding Research Group, Indonesian Oil Palm Research InstituteForestry Technology Research Group, School of Life Sciences and Technology, Bandung Institute of TechnologyDepartment of Biochemical Engineering, University College LondonResearch Center for Vaccine and Drug, National Research and Innovation AgencyPlant Science and Biotechnology Research Group, School of Life Sciences and Technology, Bandung Institute of TechnologyAbstract Increasing population and climate change pose significant threats to global food security by imposing stresses on plants, making them more susceptible to diseases and productivity losses caused by pathogens, pests, and weeds. Traditional breeding strategies are insufficient for rapid development of new plant traits that can outpace this productivity downtrend. Modern advances in genome editing technologies, particularly CRISPR/Cas9, have revolutionised crop protection through precise and targeted genome modifications. This allows for the development of resilient crops with enhanced resistance against pathogens, pests, and weeds. This review explores various approaches with which CRISPR/Cas9 is applied for crop protection: knocking out of susceptibility genes, introduction of resistance genes, and modulation of defence genes. Potential applications of CRISPR/Cas9 in crop protection include the introduction of genes conferring resistance to pathogens, disruption of insect genes responsible for survival and reproduction and engineering of herbicide-resistant crops. In conclusion, CRISPR/Cas9 holds great promises in advancing crop protection and thus ensuring food security amidst environmental and population pressures. This review highlights the transformative potential of genome editing in crop protection and calls for continued research and development in this field.https://doi.org/10.1007/s44279-024-00124-0CRISPR/Cas9Crop protectionDisease resistanceSustainable agricultureGenome editing
spellingShingle Ahmad Faizal
Syarul Nugroho
Anca Awal Sembada
Yohanes Theda
Tinta Komariyah
Rizkita Rachmi Esyanti
Genome editing in future crop protection: utilizing CRISPR/Cas9 to improve crop resistance against diseases, pests, and weeds
Discover Agriculture
CRISPR/Cas9
Crop protection
Disease resistance
Sustainable agriculture
Genome editing
title Genome editing in future crop protection: utilizing CRISPR/Cas9 to improve crop resistance against diseases, pests, and weeds
title_full Genome editing in future crop protection: utilizing CRISPR/Cas9 to improve crop resistance against diseases, pests, and weeds
title_fullStr Genome editing in future crop protection: utilizing CRISPR/Cas9 to improve crop resistance against diseases, pests, and weeds
title_full_unstemmed Genome editing in future crop protection: utilizing CRISPR/Cas9 to improve crop resistance against diseases, pests, and weeds
title_short Genome editing in future crop protection: utilizing CRISPR/Cas9 to improve crop resistance against diseases, pests, and weeds
title_sort genome editing in future crop protection utilizing crispr cas9 to improve crop resistance against diseases pests and weeds
topic CRISPR/Cas9
Crop protection
Disease resistance
Sustainable agriculture
Genome editing
url https://doi.org/10.1007/s44279-024-00124-0
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