Sexual behaviors and risk of extended-spectrum β-lactamase-producing Enterobacterales carriage: A cross-sectional analysis
Objectives: Sexual transmission of extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) is suspected. We aimed to identify clusters of sexual behavior associated with ESBL-E carriage among individuals at risk of sexually transmitted infections (STI). Methods: In this cross-sectional stu...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | International Journal of Infectious Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971224003485 |
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| author | Anders Boyd Pauline Mathieu Ugo Françoise Hayette Rougier Thibault Chiarabini Nadia Valin Karine Lacombe Paul-Louis Woerther Laure Surgers |
| author_facet | Anders Boyd Pauline Mathieu Ugo Françoise Hayette Rougier Thibault Chiarabini Nadia Valin Karine Lacombe Paul-Louis Woerther Laure Surgers |
| author_sort | Anders Boyd |
| collection | DOAJ |
| description | Objectives: Sexual transmission of extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) is suspected. We aimed to identify clusters of sexual behavior associated with ESBL-E carriage among individuals at risk of sexually transmitted infections (STI). Methods: In this cross-sectional study, patients attending an STI-screening center and human immunodeficiency virus outpatient clinic in Paris, France between 2018 and 2019 were asked questions on the following sexual activities in the last 6 months: receptive/insertive anal intercourse, passive/active rimming, receptive/insertive fellatio, receptive/insertive fisting, receptive/insertive fingering, active/passive cunnilingus. ESBL-E carriage was determined from rectal swabs. Bayesian latent class analysis was used to identify clusters of sexual activity, which were then associated with ESBL-E carriage using logistic regression. Results: Among 1211 men who have sex with men (MSM), those belonging to two latent classes with higher prevalence of insertive fingering and active rimming (ESBL-E prevalence=15.3%, N = 124 and 16.0%, N = 100) and one class with higher proportions of all behaviors (24.3%, N = 70) had a higher risk of ESBL-E carriage compared to those in a class with few sexual behaviors (7.3%, N = 259) after adjustment. Among 439 other men and 479 women, no clear associations between sexual clusters and ESBL-E carriage were observed. Conclusions: Sexual behaviors are associated with varying degrees of ESBL-E carriage, particularly among MSM. |
| format | Article |
| id | doaj-art-f29a0b2f511c43d6af827b2a63162e45 |
| institution | Kabale University |
| issn | 1201-9712 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj-art-f29a0b2f511c43d6af827b2a63162e452024-11-29T06:23:12ZengElsevierInternational Journal of Infectious Diseases1201-97122024-12-01149107277Sexual behaviors and risk of extended-spectrum β-lactamase-producing Enterobacterales carriage: A cross-sectional analysisAnders Boyd0Pauline Mathieu1Ugo Françoise2Hayette Rougier3Thibault Chiarabini4Nadia Valin5Karine Lacombe6Paul-Louis Woerther7Laure Surgers8Sorbonne Université, INSERM, Institut Pierre Louis d’Épidémiologie et de Santé Publique, Paris, France; Stichting HIV Monitoring, Amsterdam, The Netherlands; Department of Infectious Diseases, Research and Prevention, Public Health Service of Amsterdam, Amsterdam, The NetherlandsSorbonne Université, INSERM, Institut Pierre Louis d’Épidémiologie et de Santé Publique, Paris, FranceGHU AP-HP, Sorbonne Université, Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, Paris, FranceInstitut de Médecine et d'Epidémiologie Appliquée, Paris, FranceGHU AP-HP, Sorbonne Université, Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, Paris, FranceGHU AP-HP, Sorbonne Université, Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, Paris, FranceSorbonne Université, INSERM, Institut Pierre Louis d’Épidémiologie et de Santé Publique, Paris, France; GHU AP-HP, Sorbonne Université, Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, Paris, FranceUnité de Bactériologie, Département de Prévention, Diagnostic et Traitement des Infections, CHU Henri Mondor, AP-HP, Créteil, France; EA DYNAMiC 7380, Faculté de Santé, Univ Paris-Est Créteil, Créteil, FranceSorbonne Université, INSERM, Institut Pierre Louis d’Épidémiologie et de Santé Publique, Paris, France; GHU AP-HP, Sorbonne Université, Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, Paris, France; Corresponding author: Laure Surgers, Service des Maladies Infectieuses et Tropicales, AP-HP Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France.Objectives: Sexual transmission of extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) is suspected. We aimed to identify clusters of sexual behavior associated with ESBL-E carriage among individuals at risk of sexually transmitted infections (STI). Methods: In this cross-sectional study, patients attending an STI-screening center and human immunodeficiency virus outpatient clinic in Paris, France between 2018 and 2019 were asked questions on the following sexual activities in the last 6 months: receptive/insertive anal intercourse, passive/active rimming, receptive/insertive fellatio, receptive/insertive fisting, receptive/insertive fingering, active/passive cunnilingus. ESBL-E carriage was determined from rectal swabs. Bayesian latent class analysis was used to identify clusters of sexual activity, which were then associated with ESBL-E carriage using logistic regression. Results: Among 1211 men who have sex with men (MSM), those belonging to two latent classes with higher prevalence of insertive fingering and active rimming (ESBL-E prevalence=15.3%, N = 124 and 16.0%, N = 100) and one class with higher proportions of all behaviors (24.3%, N = 70) had a higher risk of ESBL-E carriage compared to those in a class with few sexual behaviors (7.3%, N = 259) after adjustment. Among 439 other men and 479 women, no clear associations between sexual clusters and ESBL-E carriage were observed. Conclusions: Sexual behaviors are associated with varying degrees of ESBL-E carriage, particularly among MSM.http://www.sciencedirect.com/science/article/pii/S1201971224003485Antimicrobial resistanceEnterobacteralesSexually transmitted diseasesTransmissionEpidemiology |
| spellingShingle | Anders Boyd Pauline Mathieu Ugo Françoise Hayette Rougier Thibault Chiarabini Nadia Valin Karine Lacombe Paul-Louis Woerther Laure Surgers Sexual behaviors and risk of extended-spectrum β-lactamase-producing Enterobacterales carriage: A cross-sectional analysis International Journal of Infectious Diseases Antimicrobial resistance Enterobacterales Sexually transmitted diseases Transmission Epidemiology |
| title | Sexual behaviors and risk of extended-spectrum β-lactamase-producing Enterobacterales carriage: A cross-sectional analysis |
| title_full | Sexual behaviors and risk of extended-spectrum β-lactamase-producing Enterobacterales carriage: A cross-sectional analysis |
| title_fullStr | Sexual behaviors and risk of extended-spectrum β-lactamase-producing Enterobacterales carriage: A cross-sectional analysis |
| title_full_unstemmed | Sexual behaviors and risk of extended-spectrum β-lactamase-producing Enterobacterales carriage: A cross-sectional analysis |
| title_short | Sexual behaviors and risk of extended-spectrum β-lactamase-producing Enterobacterales carriage: A cross-sectional analysis |
| title_sort | sexual behaviors and risk of extended spectrum β lactamase producing enterobacterales carriage a cross sectional analysis |
| topic | Antimicrobial resistance Enterobacterales Sexually transmitted diseases Transmission Epidemiology |
| url | http://www.sciencedirect.com/science/article/pii/S1201971224003485 |
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