Evaluation of Atrioventricular Valve Regurgitation in Detection of Atrioventricular Septal Defects at First Trimester Ultrasound
Objective. To assess the effectiveness of atrioventricular valve regurgitation (AVVR) detection using color Doppler in the four-chamber view (4CV) for identifying atrioventricular septal defects (AVSDs) during 11–13 + 6 weeks’ gestation. This study compares AVVR detection to conventional 2D ultrasou...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | International Journal of Clinical Practice |
| Online Access: | http://dx.doi.org/10.1155/2024/5027009 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841561527782473728 |
|---|---|
| author | Zhen Guo Yang Yan Yang Zhili Xiao Juhua Xiao Xiaojuan Chen Jia Luo Haiyan Zhou Xin |
| author_facet | Zhen Guo Yang Yan Yang Zhili Xiao Juhua Xiao Xiaojuan Chen Jia Luo Haiyan Zhou Xin |
| author_sort | Zhen Guo |
| collection | DOAJ |
| description | Objective. To assess the effectiveness of atrioventricular valve regurgitation (AVVR) detection using color Doppler in the four-chamber view (4CV) for identifying atrioventricular septal defects (AVSDs) during 11–13 + 6 weeks’ gestation. This study compares AVVR detection to conventional 2D ultrasound and investigates associations between AVSD and increased nuchal translucency thickness (NT), as well as additional cardiac, extracardiac, and chromosomal abnormalities in the first trimester. Materials and Methods. This prospective study analyzed data from singleton pregnancies diagnosed with AVSD at 11–13 weeks gestation. It included routine ultrasound examinations focusing on fetal anatomy, NT measurement, and blood flow analysis across AVVR using both color and directional power Doppler. Evaluations targeted the 4CV and the three-vessel and trachea views (3VT). Ratios such as LAVV/RAVV and main pulmonary artery-to-aorta (PA/AO) diameter were also calculated. Results. Over three years, 452 fetuses were diagnosed with congenital heart disease in the first trimester, including 25 cases of AVSD (21 complete, 1 partial, and 3 intermediate). Seventeen cases were isolated AVSDs, 13 associated with heterotaxia syndrome, one with tetralogy of Fallot, and two survived. Among these, 92% showed AVVR, 61.54% had NT above the 95th percentile, and 32.0% lacked a nasal bone. AVVR was a more reliable indicator of AVSD than other ultrasonic markers. Conclusion. AVSD exhibits a diverse range of clinical presentations. A comprehensive review of both intracardiac and extracardiac anomalies is essential. AVVR detected during NT scanning in the first trimester can confirm the presence of AVSD. |
| format | Article |
| id | doaj-art-f2816a7f1e4240a881fd8597cc6f6c19 |
| institution | Kabale University |
| issn | 1742-1241 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Clinical Practice |
| spelling | doaj-art-f2816a7f1e4240a881fd8597cc6f6c192025-01-03T01:35:15ZengWileyInternational Journal of Clinical Practice1742-12412024-01-01202410.1155/2024/5027009Evaluation of Atrioventricular Valve Regurgitation in Detection of Atrioventricular Septal Defects at First Trimester UltrasoundZhen Guo0Yang Yan1Yang Zhili2Xiao Juhua3Xiao Xiaojuan4Chen Jia5Luo Haiyan6Zhou Xin7Department of UltrasoundDepartment of Prenatal DiagnosisDepartment of UltrasoundDepartment of UltrasoundDepartment of UltrasoundDepartment of Reproduction Medicine CenterDepartment of Prenatal DiagnosisDepartment of UltrasoundObjective. To assess the effectiveness of atrioventricular valve regurgitation (AVVR) detection using color Doppler in the four-chamber view (4CV) for identifying atrioventricular septal defects (AVSDs) during 11–13 + 6 weeks’ gestation. This study compares AVVR detection to conventional 2D ultrasound and investigates associations between AVSD and increased nuchal translucency thickness (NT), as well as additional cardiac, extracardiac, and chromosomal abnormalities in the first trimester. Materials and Methods. This prospective study analyzed data from singleton pregnancies diagnosed with AVSD at 11–13 weeks gestation. It included routine ultrasound examinations focusing on fetal anatomy, NT measurement, and blood flow analysis across AVVR using both color and directional power Doppler. Evaluations targeted the 4CV and the three-vessel and trachea views (3VT). Ratios such as LAVV/RAVV and main pulmonary artery-to-aorta (PA/AO) diameter were also calculated. Results. Over three years, 452 fetuses were diagnosed with congenital heart disease in the first trimester, including 25 cases of AVSD (21 complete, 1 partial, and 3 intermediate). Seventeen cases were isolated AVSDs, 13 associated with heterotaxia syndrome, one with tetralogy of Fallot, and two survived. Among these, 92% showed AVVR, 61.54% had NT above the 95th percentile, and 32.0% lacked a nasal bone. AVVR was a more reliable indicator of AVSD than other ultrasonic markers. Conclusion. AVSD exhibits a diverse range of clinical presentations. A comprehensive review of both intracardiac and extracardiac anomalies is essential. AVVR detected during NT scanning in the first trimester can confirm the presence of AVSD.http://dx.doi.org/10.1155/2024/5027009 |
| spellingShingle | Zhen Guo Yang Yan Yang Zhili Xiao Juhua Xiao Xiaojuan Chen Jia Luo Haiyan Zhou Xin Evaluation of Atrioventricular Valve Regurgitation in Detection of Atrioventricular Septal Defects at First Trimester Ultrasound International Journal of Clinical Practice |
| title | Evaluation of Atrioventricular Valve Regurgitation in Detection of Atrioventricular Septal Defects at First Trimester Ultrasound |
| title_full | Evaluation of Atrioventricular Valve Regurgitation in Detection of Atrioventricular Septal Defects at First Trimester Ultrasound |
| title_fullStr | Evaluation of Atrioventricular Valve Regurgitation in Detection of Atrioventricular Septal Defects at First Trimester Ultrasound |
| title_full_unstemmed | Evaluation of Atrioventricular Valve Regurgitation in Detection of Atrioventricular Septal Defects at First Trimester Ultrasound |
| title_short | Evaluation of Atrioventricular Valve Regurgitation in Detection of Atrioventricular Septal Defects at First Trimester Ultrasound |
| title_sort | evaluation of atrioventricular valve regurgitation in detection of atrioventricular septal defects at first trimester ultrasound |
| url | http://dx.doi.org/10.1155/2024/5027009 |
| work_keys_str_mv | AT zhenguo evaluationofatrioventricularvalveregurgitationindetectionofatrioventricularseptaldefectsatfirsttrimesterultrasound AT yangyan evaluationofatrioventricularvalveregurgitationindetectionofatrioventricularseptaldefectsatfirsttrimesterultrasound AT yangzhili evaluationofatrioventricularvalveregurgitationindetectionofatrioventricularseptaldefectsatfirsttrimesterultrasound AT xiaojuhua evaluationofatrioventricularvalveregurgitationindetectionofatrioventricularseptaldefectsatfirsttrimesterultrasound AT xiaoxiaojuan evaluationofatrioventricularvalveregurgitationindetectionofatrioventricularseptaldefectsatfirsttrimesterultrasound AT chenjia evaluationofatrioventricularvalveregurgitationindetectionofatrioventricularseptaldefectsatfirsttrimesterultrasound AT luohaiyan evaluationofatrioventricularvalveregurgitationindetectionofatrioventricularseptaldefectsatfirsttrimesterultrasound AT zhouxin evaluationofatrioventricularvalveregurgitationindetectionofatrioventricularseptaldefectsatfirsttrimesterultrasound |