Gynostemma pentaphyllum: A review on its traditional uses, phytochemistry and pharmacology
Gynostemma pentaphyllum (GP), recognized as both an edible vegetable and health tea, has been consumed for thousands of years. Chemical research indicates GP primarily contains active ingredients including saponins, polysaccharides, and flavonoids. Notably, saponins and polysaccharides are among the...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Journal of Functional Foods |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464624006546 |
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| author | Xiujuan Li Lun Liu Song Wei |
| author_facet | Xiujuan Li Lun Liu Song Wei |
| author_sort | Xiujuan Li |
| collection | DOAJ |
| description | Gynostemma pentaphyllum (GP), recognized as both an edible vegetable and health tea, has been consumed for thousands of years. Chemical research indicates GP primarily contains active ingredients including saponins, polysaccharides, and flavonoids. Notably, saponins and polysaccharides are among the main active components of GP, which have been extensively utilized in medicine, food, healthcare, and cosmetics due to their bioactivities including anti-tumor, anti-oxidation, hypoglycemic, cardioprotective, neuroprotective and anti-inflammatory activities. We conducted searches in various online databases, including Elsevier, Springer, PubMed, Web of Science, and China Knowledge Network (CNKI), to gather literature on the traditional uses, structural characteristics, and biological activities of the active ingredients of GP published prior to October 2024. In this review, GP saponins were categorized and GP polysaccharides discovered in the last ten years were highlighted. Then, the bioactivities of GP are summarized and lays a solid foundation for its development as a functional health food. |
| format | Article |
| id | doaj-art-f2152f7d0c00409db0eaf8ead279a04c |
| institution | Kabale University |
| issn | 1756-4646 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj-art-f2152f7d0c00409db0eaf8ead279a04c2025-01-12T05:24:48ZengElsevierJournal of Functional Foods1756-46462025-01-01124106651Gynostemma pentaphyllum: A review on its traditional uses, phytochemistry and pharmacologyXiujuan Li0Lun Liu1Song Wei2Pharmaceutical Department, The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China.Pharmaceutical Department, The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China.Tumor Precise Intervention and Translational Medicine Laboratory, The Affiliated Taian City Central Hospital of Qingdao University, Taian 271000, China.; Corresponding author.Gynostemma pentaphyllum (GP), recognized as both an edible vegetable and health tea, has been consumed for thousands of years. Chemical research indicates GP primarily contains active ingredients including saponins, polysaccharides, and flavonoids. Notably, saponins and polysaccharides are among the main active components of GP, which have been extensively utilized in medicine, food, healthcare, and cosmetics due to their bioactivities including anti-tumor, anti-oxidation, hypoglycemic, cardioprotective, neuroprotective and anti-inflammatory activities. We conducted searches in various online databases, including Elsevier, Springer, PubMed, Web of Science, and China Knowledge Network (CNKI), to gather literature on the traditional uses, structural characteristics, and biological activities of the active ingredients of GP published prior to October 2024. In this review, GP saponins were categorized and GP polysaccharides discovered in the last ten years were highlighted. Then, the bioactivities of GP are summarized and lays a solid foundation for its development as a functional health food.http://www.sciencedirect.com/science/article/pii/S1756464624006546Gynostemma pentaphyllumPolysaccharidesSaponinsActive componentsBiological activitiesApplications |
| spellingShingle | Xiujuan Li Lun Liu Song Wei Gynostemma pentaphyllum: A review on its traditional uses, phytochemistry and pharmacology Journal of Functional Foods Gynostemma pentaphyllum Polysaccharides Saponins Active components Biological activities Applications |
| title | Gynostemma pentaphyllum: A review on its traditional uses, phytochemistry and pharmacology |
| title_full | Gynostemma pentaphyllum: A review on its traditional uses, phytochemistry and pharmacology |
| title_fullStr | Gynostemma pentaphyllum: A review on its traditional uses, phytochemistry and pharmacology |
| title_full_unstemmed | Gynostemma pentaphyllum: A review on its traditional uses, phytochemistry and pharmacology |
| title_short | Gynostemma pentaphyllum: A review on its traditional uses, phytochemistry and pharmacology |
| title_sort | gynostemma pentaphyllum a review on its traditional uses phytochemistry and pharmacology |
| topic | Gynostemma pentaphyllum Polysaccharides Saponins Active components Biological activities Applications |
| url | http://www.sciencedirect.com/science/article/pii/S1756464624006546 |
| work_keys_str_mv | AT xiujuanli gynostemmapentaphyllumareviewonitstraditionalusesphytochemistryandpharmacology AT lunliu gynostemmapentaphyllumareviewonitstraditionalusesphytochemistryandpharmacology AT songwei gynostemmapentaphyllumareviewonitstraditionalusesphytochemistryandpharmacology |