In pancreatic cancer, chemotherapy increases antitumor responses to tumor-associated antigens and potentiates DNA vaccination

In pancreatic cancer, chemotherapy increases antitumor responses to tumor-associated antigens and potentiates DNA vaccination

Background Pancreatic ductal adenocarcinoma (PDA) is an almost incurable tumor that is mostly resistant to chemotherapy (CT). Adaptive immune responses to tumor-associated antigens (TAA) have been reported, but immunotherapy (IT) clinical trials have not yet achieved any significant increase in surv...

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Bibliographic Details
Main Authors: Paola Cappello, Francesco Novelli, Giorgia Mandili, Claudia Curcio, Sara Bulfamante, Laura Follia, Giulio Ferrero, Emanuela Mazza, Moitza Principe, Francesca Cordero, Maria Antonietta Satolli, Rosella Spadi, Andrea Evangelista, Daniele Giordano, Duy Viet
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e001071.full
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