Febrile Infection-related Epilepsy Syndrome Treated by Vagus Nerve Stimulation and Ketonic Diet
Background: Febrile infection-related epilepsy syndrome is a refractory epilepsy syndrome that predominantly affects children, with a higher incidence in school-age children and is associated with infectious factors. Case report: A 6-year-old boy developed sudden symptoms characterized by fever and...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2024-07-01
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| Series: | Journal of Pediatrics Review |
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| Online Access: | http://jpr.mazums.ac.ir/article-1-656-en.pdf |
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| author | Yongjing Guo Wanxu Guo Jinpu Zhang Lifang Lin Rong Fu Yunfeng Zhang |
| author_facet | Yongjing Guo Wanxu Guo Jinpu Zhang Lifang Lin Rong Fu Yunfeng Zhang |
| author_sort | Yongjing Guo |
| collection | DOAJ |
| description | Background: Febrile infection-related epilepsy syndrome is a refractory epilepsy syndrome that predominantly affects children, with a higher incidence in school-age children and is associated with infectious factors.
Case report: A 6-year-old boy developed sudden symptoms characterized by fever and a disorder of consciousness, rapidly progressing into drug-refractory status epilepticus (SE). The electroencephalogram revealed diffuse slow-wave activity in the background, with partial seizures originating from the left temporal and occipital regions that gradually generalized. Brain MRI showed no abnormalities in the signal. Due to the failure of multi-drug anti-epileptic therapy, a ketogenic diet was administered and the frequency of seizure was reduced, however, a ketogenic diet was administered, which reduced the frequency of seizures; however, the ketogenic diet treatment was discontinued due to intolerance. After discharge, both the ketogenic diet and anti-seizure medications (ASMs) were administered to the patient. Upon follow-up, occasional seizures were reported, accompanied by unconsciousness and a significant decline in cognitive function compared to the pre-onset period.
Conclusions: No specific treatment modality is available for febrile infection-related epilepsy syndrome; however, a ketogenic diet and vagus nerve stimulation (VNS) may offer potential efficacy in controlling acute seizures and improving prognosis. |
| format | Article |
| id | doaj-art-f1cc9c65d5154a14a308d13a3adb6d97 |
| institution | Kabale University |
| issn | 2322-4398 2322-4401 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Pediatrics Review |
| spelling | doaj-art-f1cc9c65d5154a14a308d13a3adb6d972024-12-06T07:13:41ZengMazandaran University of Medical SciencesJournal of Pediatrics Review2322-43982322-44012024-07-01123253260Febrile Infection-related Epilepsy Syndrome Treated by Vagus Nerve Stimulation and Ketonic DietYongjing Guo0Wanxu Guo1Jinpu Zhang2Lifang Lin3Rong Fu4Yunfeng Zhang5 Department of Neonatology, The Second Hospital of Jilin University, Changchun, China. Department of Neonatology, The Second Hospital of Jilin University, Changchun, China. Department of Neonatology, The Second Hospital of Jilin University, Changchun, China. Department of Neonatology, The Second Hospital of Jilin University, Changchun, China. Department of Neonatology, The Second Hospital of Jilin University, Changchun, China. Department of Neonatology, The Second Hospital of Jilin University, Changchun, China. Background: Febrile infection-related epilepsy syndrome is a refractory epilepsy syndrome that predominantly affects children, with a higher incidence in school-age children and is associated with infectious factors. Case report: A 6-year-old boy developed sudden symptoms characterized by fever and a disorder of consciousness, rapidly progressing into drug-refractory status epilepticus (SE). The electroencephalogram revealed diffuse slow-wave activity in the background, with partial seizures originating from the left temporal and occipital regions that gradually generalized. Brain MRI showed no abnormalities in the signal. Due to the failure of multi-drug anti-epileptic therapy, a ketogenic diet was administered and the frequency of seizure was reduced, however, a ketogenic diet was administered, which reduced the frequency of seizures; however, the ketogenic diet treatment was discontinued due to intolerance. After discharge, both the ketogenic diet and anti-seizure medications (ASMs) were administered to the patient. Upon follow-up, occasional seizures were reported, accompanied by unconsciousness and a significant decline in cognitive function compared to the pre-onset period. Conclusions: No specific treatment modality is available for febrile infection-related epilepsy syndrome; however, a ketogenic diet and vagus nerve stimulation (VNS) may offer potential efficacy in controlling acute seizures and improving prognosis.http://jpr.mazums.ac.ir/article-1-656-en.pdfseizurestatus epilepticus (se)ketogenic dietvagus nerve stimulation (vns) |
| spellingShingle | Yongjing Guo Wanxu Guo Jinpu Zhang Lifang Lin Rong Fu Yunfeng Zhang Febrile Infection-related Epilepsy Syndrome Treated by Vagus Nerve Stimulation and Ketonic Diet Journal of Pediatrics Review seizure status epilepticus (se) ketogenic diet vagus nerve stimulation (vns) |
| title | Febrile Infection-related Epilepsy Syndrome Treated by Vagus Nerve Stimulation and Ketonic Diet |
| title_full | Febrile Infection-related Epilepsy Syndrome Treated by Vagus Nerve Stimulation and Ketonic Diet |
| title_fullStr | Febrile Infection-related Epilepsy Syndrome Treated by Vagus Nerve Stimulation and Ketonic Diet |
| title_full_unstemmed | Febrile Infection-related Epilepsy Syndrome Treated by Vagus Nerve Stimulation and Ketonic Diet |
| title_short | Febrile Infection-related Epilepsy Syndrome Treated by Vagus Nerve Stimulation and Ketonic Diet |
| title_sort | febrile infection related epilepsy syndrome treated by vagus nerve stimulation and ketonic diet |
| topic | seizure status epilepticus (se) ketogenic diet vagus nerve stimulation (vns) |
| url | http://jpr.mazums.ac.ir/article-1-656-en.pdf |
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