From spots to cells: Cell segmentation in spatial transcriptomics with BOMS.

From spots to cells: Cell segmentation in spatial transcriptomics with BOMS.

Imaging-based Spatial Transcriptomics methods enable the study of gene expression and regulation in complex tissues at subcellular resolution. However, inaccurate cell segmentation procedures lead to misassignment of mRNAs to individual cells which can introduce errors in downstream analysis. Curren...

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Bibliographic Details
Main Authors: Ocima Kamboj, Jeongbin Park, Oliver Stegle, Fred A Hamprecht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0311458
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