Protocol for a multicentre prehospital randomised controlled trial investigating tranexamic acid in severe trauma: the PATCH-Trauma trial

Protocol for a multicentre prehospital randomised controlled trial investigating tranexamic acid in severe trauma: the PATCH-Trauma trial

Introduction Haemorrhage causes most preventable prehospital trauma deaths and about a third of in-hospital trauma deaths. Tranexamic acid (TXA), administered soon after hospital arrival in certain trauma systems, is an effective therapy in preventing or managing acute traumatic coagulopathy. Howeve...

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Main Authors: Stephen Bernard, Ann-Marie Baker, Peter Cameron, Mark Fitzgerald, Andrew Forbes, Paul Young, Colin McArthur, Paul S Myles, Russell Gruen, Biswadev Mitra, Russell L Gruen, Dashiell Gantner, Marc Maegele, Lynnette Murray, Tony Trapani, Stephen Rashford, Tony Smith, Michael C Reade, Veronica Pitt, Robert Medcalf, Michael Reade, Huyen Tran, Grant Christey, Zsolt J Balogh, Anthony Trapani, Lynne Murray, Stefan Mazur, Camila Battistuzzo, Andy Swain, Jasmin Board, Nicole S Ng, Sally Hurford
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/3/e046522.full
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