Oxygen consumption and hemodynamics in Type 1 diabetes patients during stress testing

In 128 patients with Type 1 diabetes mellitus (DM-1) and 38 healthy volunteers, hemodynamic component of gas-transporting system was assessed in bicycle stress test, with permanent monitoring of О2 consumption, heart rate (HR), systolic and diastolic blood pressure (SBP, DBP). O2 pulse was calculate...

Full description

Saved in:
Bibliographic Details
Main Authors: E. I. Sokolov, Yu. I. Demidov, V. A. Dudaev
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2007-02-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2025
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849249969062543360
author E. I. Sokolov
Yu. I. Demidov
V. A. Dudaev
author_facet E. I. Sokolov
Yu. I. Demidov
V. A. Dudaev
author_sort E. I. Sokolov
collection DOAJ
description In 128 patients with Type 1 diabetes mellitus (DM-1) and 38 healthy volunteers, hemodynamic component of gas-transporting system was assessed in bicycle stress test, with permanent monitoring of О2 consumption, heart rate (HR), systolic and diastolic blood pressure (SBP, DBP). O2 pulse was calculated, and anaerobic threshold was determined. DM-1 patients were divided into three groups: Group 1 - without clinically manifested microangiopathy; Groups 2 and 3 -with initial and progressed manifestation of late diabetic syndrome. In all three groups, comparing to controls, mean peak О2 consumption and anaerobic threshold were significantly decreased. HR at peak stress was significantly lower inpatients with late diabetic complications than in controls, and О2 pulse was reduced in all three groups. During stress testing, Group 1 demonstrated significant SBP increase, Groups 2 and 3 - significant DBP increase, comparing to respective control levels. In DM-1 patients, disturbances of gas-transporting system hemodynamic component, registered during stress testing, develop before clinical microangiopathy manifestation. The latter progresses substantially during late diabetic syndrome evolution.
format Article
id doaj-art-f1842e11a3614e568f89a9a6373fbb60
institution Kabale University
issn 1560-4071
2618-7620
language Russian
publishDate 2007-02-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-f1842e11a3614e568f89a9a6373fbb602025-08-20T03:57:23Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202007-02-010121261780Oxygen consumption and hemodynamics in Type 1 diabetes patients during stress testingE. I. Sokolov0Yu. I. Demidov1V. A. Dudaev2Московский государственный медико-стоматологический университетМосковский государственный медико-стоматологический университетМосковский государственный медико-стоматологический университетIn 128 patients with Type 1 diabetes mellitus (DM-1) and 38 healthy volunteers, hemodynamic component of gas-transporting system was assessed in bicycle stress test, with permanent monitoring of О2 consumption, heart rate (HR), systolic and diastolic blood pressure (SBP, DBP). O2 pulse was calculated, and anaerobic threshold was determined. DM-1 patients were divided into three groups: Group 1 - without clinically manifested microangiopathy; Groups 2 and 3 -with initial and progressed manifestation of late diabetic syndrome. In all three groups, comparing to controls, mean peak О2 consumption and anaerobic threshold were significantly decreased. HR at peak stress was significantly lower inpatients with late diabetic complications than in controls, and О2 pulse was reduced in all three groups. During stress testing, Group 1 demonstrated significant SBP increase, Groups 2 and 3 - significant DBP increase, comparing to respective control levels. In DM-1 patients, disturbances of gas-transporting system hemodynamic component, registered during stress testing, develop before clinical microangiopathy manifestation. The latter progresses substantially during late diabetic syndrome evolution.https://russjcardiol.elpub.ru/jour/article/view/2025type 1 diabetes mellitusoxygen consumptionveloergometry
spellingShingle E. I. Sokolov
Yu. I. Demidov
V. A. Dudaev
Oxygen consumption and hemodynamics in Type 1 diabetes patients during stress testing
Российский кардиологический журнал
type 1 diabetes mellitus
oxygen consumption
veloergometry
title Oxygen consumption and hemodynamics in Type 1 diabetes patients during stress testing
title_full Oxygen consumption and hemodynamics in Type 1 diabetes patients during stress testing
title_fullStr Oxygen consumption and hemodynamics in Type 1 diabetes patients during stress testing
title_full_unstemmed Oxygen consumption and hemodynamics in Type 1 diabetes patients during stress testing
title_short Oxygen consumption and hemodynamics in Type 1 diabetes patients during stress testing
title_sort oxygen consumption and hemodynamics in type 1 diabetes patients during stress testing
topic type 1 diabetes mellitus
oxygen consumption
veloergometry
url https://russjcardiol.elpub.ru/jour/article/view/2025
work_keys_str_mv AT eisokolov oxygenconsumptionandhemodynamicsintype1diabetespatientsduringstresstesting
AT yuidemidov oxygenconsumptionandhemodynamicsintype1diabetespatientsduringstresstesting
AT vadudaev oxygenconsumptionandhemodynamicsintype1diabetespatientsduringstresstesting