Effect of zoledronic acid on muscle metabolism in mice with osteoporosis combined with sarcopenia

Effect of zoledronic acid on muscle metabolism in mice with osteoporosis combined with sarcopenia

Abstract Objective To investigate the effects of zoledronic acid on muscle metabolism in mice with osteoporosis and sarcopenia and elucidate the possible underlying mechanism. Methods Twenty-four 8-week-old male C57BL/6J mice were randomly divided into four groups: non-suspension (N-SUS), suspension...

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Bibliographic Details
Main Authors: Weilong Li, Ming Xu, Xuchao Shi, Jie Gu, Jian Guo, Yuanlin Xu, Bo Dai
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Musculoskeletal Disorders
Subjects:
Zoledronic acid
Sarcopenia
Muscle metabolism
Osteoporosis
Online Access:https://doi.org/10.1186/s12891-024-08054-0
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