AP1 Transcription Factors in Epidermal Differentiation and Skin Cancer

AP1 Transcription Factors in Epidermal Differentiation and Skin Cancer

AP1 (jun/fos) transcription factors (c-jun, junB, junD, c-fos, FosB, Fra-1, and Fra-2) are key regulators of epidermal keratinocyte survival and differentiation and important drivers of cancer development. Understanding the role of these factors in epidermis is complicated by the fact that each prot...

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Bibliographic Details
Main Authors: Richard L. Eckert, Gautam Adhikary, Christina A. Young, Ralph Jans, James F. Crish, Wen Xu, Ellen A. Rorke
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2013/537028
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