Promising horizons in achondroplasia along with the development of new drugs
Achondroplasia (ACH) is a representative skeletal disorder characterized by rhizomelic shortened limbs and short stature. ACH is classified as belonging to the fibroblast growth factor receptor 3 (FGFR3) group. The downstream signal transduction of FGFR3 consists of STAT1 and RAS/RAF/MEK/ERK pathway...
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Main Authors: | Keiichi Ozono, Takuo Kubota, Toshimi Michigami |
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Format: | Article |
Language: | English |
Published: |
The Japan Endocrine Society
2024-07-01
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Series: | Endocrine Journal |
Subjects: | |
Online Access: | https://www.jstage.jst.go.jp/article/endocrj/71/7/71_EJ24-0109/_html/-char/en |
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