PD-1 does not mark tumor-infiltrating CD8+ T cell dysfunction in human gastric cancer

PD-1 does not mark tumor-infiltrating CD8+ T cell dysfunction in human gastric cancer

Background Overexpression of programmed cell death protein 1 (PD-1) is linked to CD8+ T cell dysfunction and contributes to tumor immune escape. However, the prevalence and functional regulations of PD-1 expression on CD8+ T cells in human gastric cancer (GC) remain largely unknown.Methods Flow cyto...

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Main Authors: Ying Wang, Lina Wang, Yuan Zhuang, Yipin Lv, Yongliang Zhao, Fangyuan Mao, Yongsheng Teng, Liusheng Peng, Ping Cheng, Weisan Chen, Quanming Zou, Yang Shen, Yuan Qiu, Daiyuan Ma
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000422.full
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