Long-term Home Mechanical Ventilation of Children in İstanbul
OBJECTIVE: The aims of this multi-center study were to describe the characteristics of children receiving long-term home mechanical ventilation (HMV) in İstanbul and to compare the patients receiving non-invasive and invasive ventilation. MATERIAL AND METHODS: This cross-sectional multicenter study...
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2025-01-01
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| Series: | Thoracic Research and Practice |
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| Online Access: | https://thoracrespract.org/articles/long-term-home-mechanical-ventilation-of-children-in-istanbul/doi/ThoracResPract.2024.24042 |
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| author | Mürüvvet Yanaz Füsun Ünal Evrim Hepkaya Hakan Yazan Sinem Can Oksay Ebru Köstereli Cansu Yılmaz Yeğit Azer Kılıç Başkan Zeynep Reyhan Onay Aynur Gulieva Aslınur Soyyiğit Mine Kalyoncu Hanife Büşra Küçük Yetkin Ayhan Almala Pınar Ergenekon Emine Atağ Selçuk Uzuner Nilay Baş İkizoğlu Ayşe Ayzıt Kılınç Pınar Ay Ela Erdem Eralp Sedat Öktem Erkan Çakır Saniye Girit Zeynep Seda Uyan Haluk Çokuğraş Refika Ersu Bülent Karadağ Fazilet Karakoç |
| author_facet | Mürüvvet Yanaz Füsun Ünal Evrim Hepkaya Hakan Yazan Sinem Can Oksay Ebru Köstereli Cansu Yılmaz Yeğit Azer Kılıç Başkan Zeynep Reyhan Onay Aynur Gulieva Aslınur Soyyiğit Mine Kalyoncu Hanife Büşra Küçük Yetkin Ayhan Almala Pınar Ergenekon Emine Atağ Selçuk Uzuner Nilay Baş İkizoğlu Ayşe Ayzıt Kılınç Pınar Ay Ela Erdem Eralp Sedat Öktem Erkan Çakır Saniye Girit Zeynep Seda Uyan Haluk Çokuğraş Refika Ersu Bülent Karadağ Fazilet Karakoç |
| author_sort | Mürüvvet Yanaz |
| collection | DOAJ |
| description | OBJECTIVE: The aims of this multi-center study were to describe the characteristics of children receiving long-term home mechanical ventilation (HMV) in İstanbul and to compare the patients receiving non-invasive and invasive ventilation.
MATERIAL AND METHODS: This cross-sectional multicenter study included all children receiving long-term HMV followed by admission to six tertiary hospitals. The data were collected between May 2020 and May 2021. Demographic data and data regarding HMV were collected from the patient charts.
RESULTS: The study included 416 participants. The most common diagnoses were neuromuscular (35.1%) and neurological diseases (25.7%). Among the patients, 49.5% (n = 206) received non-invasive ventilation (NIV), whereas 50.5% (n = 210) received invasive ventilation. The median age at initiation was significantly younger in the invasive ventilation group than in the NIV group (10 vs. 41 months, P < 0.001). Most subjects in the NIV group (81.1%) received ventilation support only during sleep, whereas most subjects in the invasive ventilation group (55.7%) received continuous ventilator support (P < 0.001). In addition to ventilation support, 41.9% of the subjects in the invasive ventilation group and 28.6% in the NIV group received oxygen supplementation (P = 0.002). Within the last year, 59.1% (n = 246) of the subjects were hospitalized. The risk factors for hospitalization were invasive ventilation, continuous ventilatory support, oxygen supplementation, tube feeding, and swallowing dysfunction (P = 0.002, 0.009, <0.001, <0.001 and <0.001 respectively).
CONCLUSION: Despite the increasing use of NIV in most studies, half of the study population received invasive ventilation. Patients receiving invasive ventilation were more likely to require continuous ventilator support and oxygen supplementation and were at increased risk of hospitalization. |
| format | Article |
| id | doaj-art-f0a514c677b44fcf827be1f893b2988f |
| institution | Kabale University |
| issn | 2979-9139 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | AVES |
| record_format | Article |
| series | Thoracic Research and Practice |
| spelling | doaj-art-f0a514c677b44fcf827be1f893b2988f2025-01-13T11:07:44ZengAVESThoracic Research and Practice2979-91392025-01-01261253110.4274/ThoracResPract.2024.24042Long-term Home Mechanical Ventilation of Children in İstanbulMürüvvet Yanaz0https://orcid.org/0000-0002-1591-5735Füsun Ünal1https://orcid.org/0000-0002-2796-2694Evrim Hepkaya2https://orcid.org/0000-0003-2100-7984Hakan Yazan3https://orcid.org/0000-0002-5756-2667Sinem Can Oksay4https://orcid.org/0000-0001-9801-3181Ebru Köstereli5https://orcid.org/0000-0003-3800-5352Cansu Yılmaz Yeğit6https://orcid.org/0000-0001-8239-4776Azer Kılıç Başkan7https://orcid.org/0000-0002-7600-7909Zeynep Reyhan Onay8https://orcid.org/0000-0002-1251-6720Aynur Gulieva9https://orcid.org/0000-0002-5756-2667Aslınur Soyyiğit10https://orcid.org/0000-0002-7905-3484Mine Kalyoncu11https://orcid.org/0000-0002-4594-2822Hanife Büşra Küçük12https://orcid.org/0000-0001-5044-1101Yetkin Ayhan13https://orcid.org/0000-0002-8742-2622Almala Pınar Ergenekon14https://orcid.org/0000-0003-0228-9832Emine Atağ15https://orcid.org/0000-0003-3105-0409Selçuk Uzuner16https://orcid.org/0000-0002-7133-5452Nilay Baş İkizoğlu17https://orcid.org/0000-0002-5102-0031Ayşe Ayzıt Kılınç18https://orcid.org/0000-0002-2879-8910Pınar Ay19https://orcid.org/0000-0002-3303-1343Ela Erdem Eralp20https://orcid.org/0000-0001-8829-3431Sedat Öktem21https://orcid.org/0000-0002-7950-2067Erkan Çakır22https://orcid.org/0000-0001-8486-3310Saniye Girit23https://orcid.org/0000-0001-7556-6568Zeynep Seda Uyan24https://orcid.org/0000-0002-7540-3467Haluk Çokuğraş25https://orcid.org/0000-0002-0086-3936Refika Ersu26https://orcid.org/0000-0002-4317-2190Bülent Karadağ27https://orcid.org/0000-0003-0605-8871Fazilet Karakoç28https://orcid.org/0000-0001-8518-4715Department of Pediatric Pulmonology, Marmara University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul Medipol University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, Bezmiâlem Vakıf University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul Medeniyet University Faculty of Health Sciences, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, Koç University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, Marmara University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul Medeniyet University Faculty of Health Sciences, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, Marmara University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatrics, Bezmiâlem Vakıf University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, Marmara University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatrics, Bezmiâlem Vakıf University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul Medeniyet University Faculty of Health Sciences, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, Marmara University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul Medipol University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatrics, Bezmiâlem Vakıf University Faculty of Medicine, İstanbul, TürkiyeClinic of Pediatric Pulmonology, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, University ofDepartment of Pediatric Pulmonology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeDepartment of Public Health, Marmara University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, Marmara University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul Medipol University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstinye University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul Medeniyet University Faculty of Health Sciences, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, Koç University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, TürkiyeClinic of Respirology, University of Ottawa Children’s Hospital of Eastern Ontario, Ottawa, CanadaDepartment of Pediatric Pulmonology, Marmara University Faculty of Medicine, İstanbul, TürkiyeDepartment of Pediatric Pulmonology, Marmara University Faculty of Medicine, İstanbul, TürkiyeOBJECTIVE: The aims of this multi-center study were to describe the characteristics of children receiving long-term home mechanical ventilation (HMV) in İstanbul and to compare the patients receiving non-invasive and invasive ventilation. MATERIAL AND METHODS: This cross-sectional multicenter study included all children receiving long-term HMV followed by admission to six tertiary hospitals. The data were collected between May 2020 and May 2021. Demographic data and data regarding HMV were collected from the patient charts. RESULTS: The study included 416 participants. The most common diagnoses were neuromuscular (35.1%) and neurological diseases (25.7%). Among the patients, 49.5% (n = 206) received non-invasive ventilation (NIV), whereas 50.5% (n = 210) received invasive ventilation. The median age at initiation was significantly younger in the invasive ventilation group than in the NIV group (10 vs. 41 months, P < 0.001). Most subjects in the NIV group (81.1%) received ventilation support only during sleep, whereas most subjects in the invasive ventilation group (55.7%) received continuous ventilator support (P < 0.001). In addition to ventilation support, 41.9% of the subjects in the invasive ventilation group and 28.6% in the NIV group received oxygen supplementation (P = 0.002). Within the last year, 59.1% (n = 246) of the subjects were hospitalized. The risk factors for hospitalization were invasive ventilation, continuous ventilatory support, oxygen supplementation, tube feeding, and swallowing dysfunction (P = 0.002, 0.009, <0.001, <0.001 and <0.001 respectively). CONCLUSION: Despite the increasing use of NIV in most studies, half of the study population received invasive ventilation. Patients receiving invasive ventilation were more likely to require continuous ventilator support and oxygen supplementation and were at increased risk of hospitalization.https://thoracrespract.org/articles/long-term-home-mechanical-ventilation-of-children-in-istanbul/doi/ThoracResPract.2024.24042non-invasive ventilationneuromuscular disorderslong-term home mechanical ventilationchronic respiratory failure |
| spellingShingle | Mürüvvet Yanaz Füsun Ünal Evrim Hepkaya Hakan Yazan Sinem Can Oksay Ebru Köstereli Cansu Yılmaz Yeğit Azer Kılıç Başkan Zeynep Reyhan Onay Aynur Gulieva Aslınur Soyyiğit Mine Kalyoncu Hanife Büşra Küçük Yetkin Ayhan Almala Pınar Ergenekon Emine Atağ Selçuk Uzuner Nilay Baş İkizoğlu Ayşe Ayzıt Kılınç Pınar Ay Ela Erdem Eralp Sedat Öktem Erkan Çakır Saniye Girit Zeynep Seda Uyan Haluk Çokuğraş Refika Ersu Bülent Karadağ Fazilet Karakoç Long-term Home Mechanical Ventilation of Children in İstanbul Thoracic Research and Practice non-invasive ventilation neuromuscular disorders long-term home mechanical ventilation chronic respiratory failure |
| title | Long-term Home Mechanical Ventilation of Children in İstanbul |
| title_full | Long-term Home Mechanical Ventilation of Children in İstanbul |
| title_fullStr | Long-term Home Mechanical Ventilation of Children in İstanbul |
| title_full_unstemmed | Long-term Home Mechanical Ventilation of Children in İstanbul |
| title_short | Long-term Home Mechanical Ventilation of Children in İstanbul |
| title_sort | long term home mechanical ventilation of children in istanbul |
| topic | non-invasive ventilation neuromuscular disorders long-term home mechanical ventilation chronic respiratory failure |
| url | https://thoracrespract.org/articles/long-term-home-mechanical-ventilation-of-children-in-istanbul/doi/ThoracResPract.2024.24042 |
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