The role of oxidative stress, apoptosis and altered TRPM2 channel activation in doxorubicin-induced liver injury; the protective effect of selenium

The role of oxidative stress, apoptosis and altered TRPM2 channel activation in doxorubicin-induced liver injury; the protective effect of selenium

Aim: Doxorubicin (DOXR) is frequently used alone or as combination therapy in the treatment of various types of cancer. Although dose-dependent side effects are known, its effects on liver health are not fully known. This study aimed to investigate the role of the transient receptor potential melast...

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Bibliographic Details
Main Authors: Mehmet Hafit Bayir, Fikret Altındağ, Zübeyir Huyut, Kenan Yıldızhan
Format: Article
Language:English
Published: Alanya Alaaddin Keykubat University 2024-08-01
Series:Acta Medica Alanya
Subjects:
apoptosis
doxorubicin
hepatotoxicity
lipid profile
trpm2 channel
apoptoz
doksorubisin
hepatotoksisite
lipid profili
trpm2 kanalı
Online Access:https://dergipark.org.tr/tr/download/article-file/3926956
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