DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma

DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma

BackgroundDamage-associated molecular patterns (DAMPs) induced by immunogenic cell death (ICD) may be useful for the immunotherapy to patients undergoing pancreatic ductal adenocarcinoma (PDAC). The aim of this study is to predict the prognosis and immunotherapy responsiveness of PDAC patients using...

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Bibliographic Details
Main Authors: Qianxue Wu, Qian Xiao, Xin Tang, Liuying Li, Daqiang Song, Yang Zhou, Benhua Li, Guosheng Ren, Fang Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
PANX1
DAMPs
PDAC
NOD1
NFκB
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1516457/full
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