Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults

Objective: Many studies are interested in the association between non-alcoholic fatty liver disease (N-AFLD) and other parameters. Our study evaluated the association between serum uric acid (SrUA) levels and N-AFLD in non-diabetic non-obese adults. Methods: In this study, 50 patients and 50 contro...

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Main Authors: Gültekin Pekcan, Hüseyin Demirci, Fahri Yakaryılmaz
Format: Article
Language:English
Published: Galenos Publishing House 2024-01-01
Series:Gazi Medical Journal
Subjects:
Online Access:https://gazimedj.com/articles/relationship-between-n-afld-and-serum-uric-acid-levels-in-non-diabetic-and-non-obese-adults/doi/gmj.galenos.2023.4034
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author Gültekin Pekcan
Hüseyin Demirci
Fahri Yakaryılmaz
author_facet Gültekin Pekcan
Hüseyin Demirci
Fahri Yakaryılmaz
author_sort Gültekin Pekcan
collection DOAJ
description Objective: Many studies are interested in the association between non-alcoholic fatty liver disease (N-AFLD) and other parameters. Our study evaluated the association between serum uric acid (SrUA) levels and N-AFLD in non-diabetic non-obese adults. Methods: In this study, 50 patients and 50 control subjects were enrolled to investigate the association between SrUA and N-AFLD in adults. The Kruskal-Wallis test was used to compare SrUA values according to ultrasonographic liver fat levels. Results: A statistically significant difference was found between the N-AFLD and control subjects according to the mean SrUA level (p<0.001). In the N-AFLD group, a positive relationship was found between SrUA levels and homeostasis model assessment of insulin resistance values (r=0.35, p<0.001). Conclusion: In this study, an important positive relationship was detected between SrUA levels and N-AFLD and insulin resistance.
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institution Kabale University
issn 2147-2092
language English
publishDate 2024-01-01
publisher Galenos Publishing House
record_format Article
series Gazi Medical Journal
spelling doaj-art-f03c6c5c3b774294bea69e739ad44cb32025-01-17T11:58:01ZengGalenos Publishing HouseGazi Medical Journal2147-20922024-01-01351868910.12996/gmj.galenos.2023.4034Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese AdultsGültekin Pekcan0https://orcid.org/0000-0003-3245-4667Hüseyin Demirci1https://orcid.org/0000-0003-0737-2360Fahri Yakaryılmaz2https://orcid.org/0000-0002-4328-474XAnkara Bilkent City Hospital, Clinic of Hematology, Ankara, TürkiyeAnkara Etlik City Hospital, Clinic of Endocrinology, Ankara, TürkiyeAnkara Etlik City Hospital, Clinic of Gastroenterology, Ankara, TürkiyeObjective: Many studies are interested in the association between non-alcoholic fatty liver disease (N-AFLD) and other parameters. Our study evaluated the association between serum uric acid (SrUA) levels and N-AFLD in non-diabetic non-obese adults. Methods: In this study, 50 patients and 50 control subjects were enrolled to investigate the association between SrUA and N-AFLD in adults. The Kruskal-Wallis test was used to compare SrUA values according to ultrasonographic liver fat levels. Results: A statistically significant difference was found between the N-AFLD and control subjects according to the mean SrUA level (p<0.001). In the N-AFLD group, a positive relationship was found between SrUA levels and homeostasis model assessment of insulin resistance values (r=0.35, p<0.001). Conclusion: In this study, an important positive relationship was detected between SrUA levels and N-AFLD and insulin resistance.https://gazimedj.com/articles/relationship-between-n-afld-and-serum-uric-acid-levels-in-non-diabetic-and-non-obese-adults/doi/gmj.galenos.2023.4034n-afldnon-diabeticnon-obeseserum uric acidhomairmetabolic syndrome
spellingShingle Gültekin Pekcan
Hüseyin Demirci
Fahri Yakaryılmaz
Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults
Gazi Medical Journal
n-afld
non-diabetic
non-obese
serum uric acid
homair
metabolic syndrome
title Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults
title_full Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults
title_fullStr Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults
title_full_unstemmed Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults
title_short Relationship Between N-AFLD and Serum Uric Acid Levels in Non-Diabetic and Non- Obese Adults
title_sort relationship between n afld and serum uric acid levels in non diabetic and non obese adults
topic n-afld
non-diabetic
non-obese
serum uric acid
homair
metabolic syndrome
url https://gazimedj.com/articles/relationship-between-n-afld-and-serum-uric-acid-levels-in-non-diabetic-and-non-obese-adults/doi/gmj.galenos.2023.4034
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AT huseyindemirci relationshipbetweennafldandserumuricacidlevelsinnondiabeticandnonobeseadults
AT fahriyakaryılmaz relationshipbetweennafldandserumuricacidlevelsinnondiabeticandnonobeseadults