Super-enhancers in hepatocellular carcinoma: regulatory mechanism and therapeutic targets

Super-enhancers in hepatocellular carcinoma: regulatory mechanism and therapeutic targets

Abstract Super-enhancers (SEs) represent a distinct category of cis-regulatory elements notable for their robust transcriptional activation capabilities. In tumor cells, SEs intricately regulate the expression of oncogenes and pivotal cancer-associated signaling pathways, offering significant potent...

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Bibliographic Details
Main Authors: Xuejin Lu, Meizi Zhu, Xingyue Pei, Jinhu Ma, Rui Wang, Yi Wang, Shuwen Chen, Yan Yan, Yaling Zhu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cancer Cell International
Subjects:
Hepatocellular carcinoma
Super-enhancer
Therapeutic targets
Online Access:https://doi.org/10.1186/s12935-024-03599-5
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