Improvement of liver involvement in familial Mediterranean fever after introduction of canakinumab: a case report

Improvement of liver involvement in familial Mediterranean fever after introduction of canakinumab: a case report

A 44-year-old Jewish woman with familial Mediterranean fever (FMF) developed non-alcoholic steato-hepatitis during colchicine treatment (2,5 mg per day), confirmed by both elastographic study and liver biopsy. A combined therapy with the interleukin-1 (IL-1) blocking agent canakinumab (150 mg every...

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Bibliographic Details
Main Authors: Maria Grazia Massaro, Maurizio Pompili, Ludovico Luca Sicignano, Fabrizio Pizzolante, Elena Verrecchia, Fabio Maria Vecchio, Donato Rigante, Raffaele Manna
Format: Article
Language:English
Published: PAGEPress Publications 2020-08-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Familial Mediterranean fever, autoinflammation, periodic fever, steatosis, hepatitis, colchicine, interleukin-1, innovative biotechnologies, anakinra, canakinumab, personalized medicine
Online Access:https://www.mjhid.org/index.php/mjhid/article/view/4272
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