Gelsolin-mediated actin filament severing, mechanics, and conformational changes at neutral and acidic pH
Gelsolin is a calcium (Ca2+) dependent, pH sensitive actin-binding protein that regulates actin filament dynamics to remodel the actin cytoskeleton. It is known that gelsolin binding induces conformational changes of actin filaments, leading to filament severing. However, the influence of physiologi...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Soft Matter |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/frsfm.2025.1530439/full |
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