Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional survey
Objectives Scant data are available on syphilis infection within migrant populations worldwide and in the population of the Middle East and North Africa region. This study investigated the prevalence of both lifetime and recent syphilis infections among migrant craft and manual workers (MCMWs) in Qa...
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BMJ Publishing Group
2024-11-01
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| author | Hiam Chemaitelly Houssein H Ayoub Hanan F Abdul Rahim Abdullatif Al Khal Einas Al Kuwari Roberto Bertollini Peter Coyle Andrew Jeremijenko Anvar Hassan Kaleeckal Gheyath K Nasrallah Hadi M Yassine Hamad Eid Al Romaihi Mohammed H Al-Thani Mohamed Ghaith Al-Kuwari Asmaa A Al Thani Ahmed Ismail Ahmed Ismail Duaa W Al-Sadeq Fathima H Amanullah Jawaher A Al-Emadi Hadiya M Khalid Parveen B Nizamuddin Ibrahim Al-Shaar Ibrahim W Karimeh Mutaz M Ali Sami Abdeen Ashraf Abdelkarim Faisal Daraan Ahmed Ibrahim Hashim Elhaj Ismail Nahid Mostafa Mohamed Sahl Jinan Suliman Elias Tayar Hasan Ali Kasem Meynard J A Agsalog Bassam K Akkarathodiyil Ayat A Alkhalaf Mohamed Morhaf M H Alakshar Abdulsalam Ali A H Al-Qahtani Monther H A Al-Shedifat Anas Ansari Ahmad Ali Ataalla Sandeep Chougule Abhilash K K V Gopinathan Feroz J Poolakundan Sanjay U Ranbhise Saed M A Saefan Mohamed M Thaivalappil Abubacker S Thoyalil Inayath M Umar Odette Chaghoury Elmoubasher Farag |
| author_facet | Hiam Chemaitelly Houssein H Ayoub Hanan F Abdul Rahim Abdullatif Al Khal Einas Al Kuwari Roberto Bertollini Peter Coyle Andrew Jeremijenko Anvar Hassan Kaleeckal Gheyath K Nasrallah Hadi M Yassine Hamad Eid Al Romaihi Mohammed H Al-Thani Mohamed Ghaith Al-Kuwari Asmaa A Al Thani Ahmed Ismail Ahmed Ismail Duaa W Al-Sadeq Fathima H Amanullah Jawaher A Al-Emadi Hadiya M Khalid Parveen B Nizamuddin Ibrahim Al-Shaar Ibrahim W Karimeh Mutaz M Ali Sami Abdeen Ashraf Abdelkarim Faisal Daraan Ahmed Ibrahim Hashim Elhaj Ismail Nahid Mostafa Mohamed Sahl Jinan Suliman Elias Tayar Hasan Ali Kasem Meynard J A Agsalog Bassam K Akkarathodiyil Ayat A Alkhalaf Mohamed Morhaf M H Alakshar Abdulsalam Ali A H Al-Qahtani Monther H A Al-Shedifat Anas Ansari Ahmad Ali Ataalla Sandeep Chougule Abhilash K K V Gopinathan Feroz J Poolakundan Sanjay U Ranbhise Saed M A Saefan Mohamed M Thaivalappil Abubacker S Thoyalil Inayath M Umar Odette Chaghoury Elmoubasher Farag |
| author_sort | Hiam Chemaitelly |
| collection | DOAJ |
| description | Objectives Scant data are available on syphilis infection within migrant populations worldwide and in the population of the Middle East and North Africa region. This study investigated the prevalence of both lifetime and recent syphilis infections among migrant craft and manual workers (MCMWs) in Qatar, a diverse demographic representing 60% of the country’s population.Methods Sera specimens collected during a nationwide cross-sectional survey of SARS-CoV-2 seroprevalence among the MCMW population, conducted between 26 July and 9 September 2020, were analysed. Treponema pallidum antibodies were detected using the Mindray CL-900i Chemiluminescence Immunoassay Analyzer. To differentiate recent infections, rapid plasma reagin (RPR) testing was performed, with an RPR titre of ≥1:8 considered indicative of recent infection. Logistic regression analyses were employed to identify factors associated with lifetime syphilis infection. Sampling weights were incorporated into all statistical analyses to obtain population-level estimates.Results T. pallidum antibodies were identified in 38 of the 2528 tested sera specimens. Prevalence of lifetime infection was estimated at 1.3% (95% CI 0.9% to 1.8%). Among the 38 treponemal-positive specimens, 15 were reactive by RPR, with three having titres ≥1:8, indicating recent infection. Prevalence of recent infection was estimated at 0.09% (95% CI 0.01 to 0.3%). Among treponemal-positive MCMWs, the estimated proportion with recent infection was 8.1% (95% CI: 1.7 to 21.4%). The adjusted OR for lifetime infection increased with age, reaching 8.68 (95% CI 2.58 to 29.23) among those aged ≥60 years compared with those ≤29 years of age. Differences in prevalence were observed by nationality and occupation, but no differences were found by educational attainment or geographic location.Conclusions Syphilis prevalence among MCMWs in Qatar is consistent with global levels, highlighting a disease burden with implications for health and social well-being. These findings underscore the need for programmes addressing both sexually transmitted infections and the broader sexual health needs of this population. |
| format | Article |
| id | doaj-art-ef98e04cde5c48e0bc493042f5c0eda2 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-ef98e04cde5c48e0bc493042f5c0eda22024-12-13T08:20:09ZengBMJ Publishing GroupBMJ Open2044-60552024-11-01141110.1136/bmjopen-2023-083810Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional surveyHiam Chemaitelly0Houssein H Ayoub1Hanan F Abdul Rahim2Abdullatif Al Khal3Einas Al Kuwari4Roberto Bertollini5Peter Coyle6Andrew Jeremijenko7Anvar Hassan Kaleeckal8Gheyath K Nasrallah9Hadi M Yassine10Hamad Eid Al Romaihi11Mohammed H Al-Thani12Mohamed Ghaith Al-Kuwari13Asmaa A Al Thani14Ahmed Ismail Ahmed Ismail15Duaa W Al-Sadeq16Fathima H Amanullah17Jawaher A Al-Emadi18Hadiya M Khalid19Parveen B Nizamuddin20Ibrahim Al-Shaar21Ibrahim W Karimeh22Mutaz M Ali23Sami Abdeen24Ashraf Abdelkarim25Faisal Daraan26Ahmed Ibrahim Hashim Elhaj Ismail27Nahid Mostafa28Mohamed Sahl29Jinan Suliman30Elias Tayar31Hasan Ali Kasem32Meynard J A Agsalog33Bassam K Akkarathodiyil34Ayat A Alkhalaf35Mohamed Morhaf M H Alakshar36Abdulsalam Ali A H Al-Qahtani37Monther H A Al-Shedifat38Anas Ansari39Ahmad Ali Ataalla40Sandeep Chougule41Abhilash K K V Gopinathan42Feroz J Poolakundan43Sanjay U Ranbhise44Saed M A Saefan45Mohamed M Thaivalappil46Abubacker S Thoyalil47Inayath M Umar48Odette Chaghoury49Elmoubasher Farag504 Department of Population Health Sciences, Weill Cornell Medicine, Cornell University, New York, New York, USA6 Mathematics Program, Department of Mathematics, Statistics, and Physics, College of Arts and Sciences, Qatar University, Doha, Qatar11 Department of Public Health, College of Health Sciences, QU Health, Qatar University, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar8 Ministry of Public Health Qatar, Doha, Qatar1 Biomedical Research Center, Qatar University, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar1 Biomedical Research Center, Qatar University, Doha, Qatar1 Biomedical Research Center, Qatar University, Doha, Qatar8 Ministry of Public Health Qatar, Doha, Qatar8 Ministry of Public Health Qatar, Doha, Qatar12 Primary Health Care Corporation, Doha, Qatar1 Biomedical Research Center, Qatar University, Doha, Qatar5 Laboratory Section, Medical Commission Department, Ministry of Public Health, Doha, Qatar1 Biomedical Research Center, Qatar University, Doha, Qatar1 Biomedical Research Center, Qatar University, Doha, Qatar1 Biomedical Research Center, Qatar University, Doha, Qatar1 Biomedical Research Center, Qatar University, Doha, Qatar1 Biomedical Research Center, Qatar University, Doha, Qatar5 Laboratory Section, Medical Commission Department, Ministry of Public Health, Doha, Qatar5 Laboratory Section, Medical Commission Department, Ministry of Public Health, Doha, Qatar5 Laboratory Section, Medical Commission Department, Ministry of Public Health, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar8 Ministry of Public Health Qatar, Doha, Qatar8 Ministry of Public Health Qatar, Doha, Qatar8 Ministry of Public Health Qatar, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar9 Qatar Red Crescent Society, Doha, Qatar7 Hamad Medical Corporation, Doha, Qatar8 Ministry of Public Health Qatar, Doha, QatarObjectives Scant data are available on syphilis infection within migrant populations worldwide and in the population of the Middle East and North Africa region. This study investigated the prevalence of both lifetime and recent syphilis infections among migrant craft and manual workers (MCMWs) in Qatar, a diverse demographic representing 60% of the country’s population.Methods Sera specimens collected during a nationwide cross-sectional survey of SARS-CoV-2 seroprevalence among the MCMW population, conducted between 26 July and 9 September 2020, were analysed. Treponema pallidum antibodies were detected using the Mindray CL-900i Chemiluminescence Immunoassay Analyzer. To differentiate recent infections, rapid plasma reagin (RPR) testing was performed, with an RPR titre of ≥1:8 considered indicative of recent infection. Logistic regression analyses were employed to identify factors associated with lifetime syphilis infection. Sampling weights were incorporated into all statistical analyses to obtain population-level estimates.Results T. pallidum antibodies were identified in 38 of the 2528 tested sera specimens. Prevalence of lifetime infection was estimated at 1.3% (95% CI 0.9% to 1.8%). Among the 38 treponemal-positive specimens, 15 were reactive by RPR, with three having titres ≥1:8, indicating recent infection. Prevalence of recent infection was estimated at 0.09% (95% CI 0.01 to 0.3%). Among treponemal-positive MCMWs, the estimated proportion with recent infection was 8.1% (95% CI: 1.7 to 21.4%). The adjusted OR for lifetime infection increased with age, reaching 8.68 (95% CI 2.58 to 29.23) among those aged ≥60 years compared with those ≤29 years of age. Differences in prevalence were observed by nationality and occupation, but no differences were found by educational attainment or geographic location.Conclusions Syphilis prevalence among MCMWs in Qatar is consistent with global levels, highlighting a disease burden with implications for health and social well-being. These findings underscore the need for programmes addressing both sexually transmitted infections and the broader sexual health needs of this population.https://bmjopen.bmj.com/content/14/11/e083810.full |
| spellingShingle | Hiam Chemaitelly Houssein H Ayoub Hanan F Abdul Rahim Abdullatif Al Khal Einas Al Kuwari Roberto Bertollini Peter Coyle Andrew Jeremijenko Anvar Hassan Kaleeckal Gheyath K Nasrallah Hadi M Yassine Hamad Eid Al Romaihi Mohammed H Al-Thani Mohamed Ghaith Al-Kuwari Asmaa A Al Thani Ahmed Ismail Ahmed Ismail Duaa W Al-Sadeq Fathima H Amanullah Jawaher A Al-Emadi Hadiya M Khalid Parveen B Nizamuddin Ibrahim Al-Shaar Ibrahim W Karimeh Mutaz M Ali Sami Abdeen Ashraf Abdelkarim Faisal Daraan Ahmed Ibrahim Hashim Elhaj Ismail Nahid Mostafa Mohamed Sahl Jinan Suliman Elias Tayar Hasan Ali Kasem Meynard J A Agsalog Bassam K Akkarathodiyil Ayat A Alkhalaf Mohamed Morhaf M H Alakshar Abdulsalam Ali A H Al-Qahtani Monther H A Al-Shedifat Anas Ansari Ahmad Ali Ataalla Sandeep Chougule Abhilash K K V Gopinathan Feroz J Poolakundan Sanjay U Ranbhise Saed M A Saefan Mohamed M Thaivalappil Abubacker S Thoyalil Inayath M Umar Odette Chaghoury Elmoubasher Farag Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional survey BMJ Open |
| title | Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional survey |
| title_full | Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional survey |
| title_fullStr | Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional survey |
| title_full_unstemmed | Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional survey |
| title_short | Prevalence of syphilis infection among migrant workers in Qatar: a nationwide cross-sectional survey |
| title_sort | prevalence of syphilis infection among migrant workers in qatar a nationwide cross sectional survey |
| url | https://bmjopen.bmj.com/content/14/11/e083810.full |
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