Effects of ginseng on TNF-α, leptin and plasma lipid levels of rats fed a cholesterol-rich diet
This study assessed the effects of ginseng root powder on plasma total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, leptin, and TNF-α levels of adult rats fed a cholesterol-rich diet. In this study, 48 healthy adult male Wistar Albino rats were divided into three groups: a control g...
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| Language: | English |
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Selcuk University Press
2014-07-01
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| Series: | Türk Spor ve Egzersiz Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/200698 |
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| author | Deniz Uluısık Ercan Keskın Mehmet Altın |
| author_facet | Deniz Uluısık Ercan Keskın Mehmet Altın |
| author_sort | Deniz Uluısık |
| collection | DOAJ |
| description | This study assessed the effects of ginseng root powder on plasma total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, leptin, and TNF-α levels of adult rats fed a cholesterol-rich diet. In this study, 48 healthy adult male Wistar Albino rats were divided into three groups: a control group (K), a cholesterol group (C), and a cholesterol+ginseng group (CG). The K group was fed a standard rat diet, whereas the C and CG groups were fed the same standard diet containing 5% cholesterol and 5% cholesterol+1 g/kg Panax ginseng root powder, respectively. Blood samples were taken on days 20 and 40 of the study. On days 20 and 40, the CG group had lower plasma total cholesterol levels than the C group (p lt;0.05). On day 20, there were no significant differences in plasma LDL-cholesterol levels between the CG and K groups. The reduction in plasma trygliceride levels (day 20), the increase in plasma HDL-cholesterol levels (day 20) and the decrease in plasma leptin levels (day 40) in the CG group compared to the C group were significant (p lt;0.05). However, there were no differences in TNF-α plasma levels on days 20 or 40 both between sampling times and among the groups. The results of this study support the use of ginseng to ameliorate abnormalities in serum lipid levels. |
| format | Article |
| id | doaj-art-ef6f0559f8684686ae7206d7e2add335 |
| institution | Kabale University |
| issn | 2147-5652 |
| language | English |
| publishDate | 2014-07-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Türk Spor ve Egzersiz Dergisi |
| spelling | doaj-art-ef6f0559f8684686ae7206d7e2add3352025-01-03T01:23:52ZengSelcuk University PressTürk Spor ve Egzersiz Dergisi2147-56522014-07-011625962154Effects of ginseng on TNF-α, leptin and plasma lipid levels of rats fed a cholesterol-rich dietDeniz UluısıkErcan KeskınMehmet AltınThis study assessed the effects of ginseng root powder on plasma total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, leptin, and TNF-α levels of adult rats fed a cholesterol-rich diet. In this study, 48 healthy adult male Wistar Albino rats were divided into three groups: a control group (K), a cholesterol group (C), and a cholesterol+ginseng group (CG). The K group was fed a standard rat diet, whereas the C and CG groups were fed the same standard diet containing 5% cholesterol and 5% cholesterol+1 g/kg Panax ginseng root powder, respectively. Blood samples were taken on days 20 and 40 of the study. On days 20 and 40, the CG group had lower plasma total cholesterol levels than the C group (p lt;0.05). On day 20, there were no significant differences in plasma LDL-cholesterol levels between the CG and K groups. The reduction in plasma trygliceride levels (day 20), the increase in plasma HDL-cholesterol levels (day 20) and the decrease in plasma leptin levels (day 40) in the CG group compared to the C group were significant (p lt;0.05). However, there were no differences in TNF-α plasma levels on days 20 or 40 both between sampling times and among the groups. The results of this study support the use of ginseng to ameliorate abnormalities in serum lipid levels.https://dergipark.org.tr/tr/download/article-file/200698ginsengcholesterolleptinadult ratstnf-α |
| spellingShingle | Deniz Uluısık Ercan Keskın Mehmet Altın Effects of ginseng on TNF-α, leptin and plasma lipid levels of rats fed a cholesterol-rich diet Türk Spor ve Egzersiz Dergisi ginseng cholesterol leptin adult rats tnf-α |
| title | Effects of ginseng on TNF-α, leptin and plasma lipid levels of rats fed a cholesterol-rich diet |
| title_full | Effects of ginseng on TNF-α, leptin and plasma lipid levels of rats fed a cholesterol-rich diet |
| title_fullStr | Effects of ginseng on TNF-α, leptin and plasma lipid levels of rats fed a cholesterol-rich diet |
| title_full_unstemmed | Effects of ginseng on TNF-α, leptin and plasma lipid levels of rats fed a cholesterol-rich diet |
| title_short | Effects of ginseng on TNF-α, leptin and plasma lipid levels of rats fed a cholesterol-rich diet |
| title_sort | effects of ginseng on tnf i leptin and plasma lipid levels of rats fed a cholesterol rich diet |
| topic | ginseng cholesterol leptin adult rats tnf-α |
| url | https://dergipark.org.tr/tr/download/article-file/200698 |
| work_keys_str_mv | AT denizuluısık effectsofginsengontnfileptinandplasmalipidlevelsofratsfedacholesterolrichdiet AT ercankeskın effectsofginsengontnfileptinandplasmalipidlevelsofratsfedacholesterolrichdiet AT mehmetaltın effectsofginsengontnfileptinandplasmalipidlevelsofratsfedacholesterolrichdiet |