Cocaine Induced Vasculitis: Have We Found a Culprit?

Cocaine abuse is relatively common in our society. To enhance profitability and acceptability of the product, it is not uncommon for illicit drugs to undergo several processes. The Drug Enforcement Agency (DEA) has reported that seventy percent (70%) of cocaine seized at USA borders has been adulter...

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Main Authors: Alfredo Sánchez-Cruz, Sylmarie Marrero, José Betancourt, Myrna Andino, Adolfo Lopez, Jose Gutierrez-Nuñez
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2012/982361
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author Alfredo Sánchez-Cruz
Sylmarie Marrero
José Betancourt
Myrna Andino
Adolfo Lopez
Jose Gutierrez-Nuñez
author_facet Alfredo Sánchez-Cruz
Sylmarie Marrero
José Betancourt
Myrna Andino
Adolfo Lopez
Jose Gutierrez-Nuñez
author_sort Alfredo Sánchez-Cruz
collection DOAJ
description Cocaine abuse is relatively common in our society. To enhance profitability and acceptability of the product, it is not uncommon for illicit drugs to undergo several processes. The Drug Enforcement Agency (DEA) has reported that seventy percent (70%) of cocaine seized at USA borders has been adulterated with levamisole, previously used as chemotherapeutic and immunomodulator for several conditions. Among the side effects of levamisole-adulterated cocaine, necrotizing vasculitis is the more dramatic. We report three cases of necrotizing vasculitis associated with antineutrophils cytoplasmic antibodies (ANCAs) positivity, linked to the use of cocaine. To our knowledge, these are the first cases of cocaine induced vasculitis reported in the Caribbean.
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issn 2090-6889
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publishDate 2012-01-01
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series Case Reports in Rheumatology
spelling doaj-art-eef6000c27b44f34a5e1b08443e8f23d2025-02-03T05:52:54ZengWileyCase Reports in Rheumatology2090-68892090-68972012-01-01201210.1155/2012/982361982361Cocaine Induced Vasculitis: Have We Found a Culprit?Alfredo Sánchez-Cruz0Sylmarie Marrero1José Betancourt2Myrna Andino3Adolfo Lopez4Jose Gutierrez-Nuñez5Department of Internal Medicine, San Juan City Hospital, San Juan, PR 00928, USADepartment of Internal Medicine, San Juan City Hospital, San Juan, PR 00928, USADepartment of Internal Medicine, San Juan City Hospital, San Juan, PR 00928, USADepartment of Internal Medicine, San Juan City Hospital, San Juan, PR 00928, USADepartment of Internal Medicine, San Juan City Hospital, San Juan, PR 00928, USADepartment of Internal Medicine, VA Caribbean Healthcare System, San Juan, PR 00921, USACocaine abuse is relatively common in our society. To enhance profitability and acceptability of the product, it is not uncommon for illicit drugs to undergo several processes. The Drug Enforcement Agency (DEA) has reported that seventy percent (70%) of cocaine seized at USA borders has been adulterated with levamisole, previously used as chemotherapeutic and immunomodulator for several conditions. Among the side effects of levamisole-adulterated cocaine, necrotizing vasculitis is the more dramatic. We report three cases of necrotizing vasculitis associated with antineutrophils cytoplasmic antibodies (ANCAs) positivity, linked to the use of cocaine. To our knowledge, these are the first cases of cocaine induced vasculitis reported in the Caribbean.http://dx.doi.org/10.1155/2012/982361
spellingShingle Alfredo Sánchez-Cruz
Sylmarie Marrero
José Betancourt
Myrna Andino
Adolfo Lopez
Jose Gutierrez-Nuñez
Cocaine Induced Vasculitis: Have We Found a Culprit?
Case Reports in Rheumatology
title Cocaine Induced Vasculitis: Have We Found a Culprit?
title_full Cocaine Induced Vasculitis: Have We Found a Culprit?
title_fullStr Cocaine Induced Vasculitis: Have We Found a Culprit?
title_full_unstemmed Cocaine Induced Vasculitis: Have We Found a Culprit?
title_short Cocaine Induced Vasculitis: Have We Found a Culprit?
title_sort cocaine induced vasculitis have we found a culprit
url http://dx.doi.org/10.1155/2012/982361
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