哌仑西平脂质体的研制及评价
【目的】 制备稳定性好?包封率高?缓释性能优的哌仑西平脂质体?【方法】采用均匀设计等方法筛选制备哌仑西平脂质体的处方和工艺,并对其形态?粒径?包封率?加速实验结果及体外释放规律进行考察?【结果】 制得的哌仑西平脂质体为单层脂质体,平均粒径为480 nm,包封率为77.24%±9.83%,其稳定性好,缓释效果优于哌仑西平磷酸缓冲液?【结论】 哌仑西平脂质体达到设计要求?...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Sun Yat-sen University
2004-01-01
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| Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
| Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/43585430/ |
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| author | 戴淑真 |
| author_facet | 戴淑真 |
| author_sort | 戴淑真 |
| collection | DOAJ |
| description | 【目的】 制备稳定性好?包封率高?缓释性能优的哌仑西平脂质体?【方法】采用均匀设计等方法筛选制备哌仑西平脂质体的处方和工艺,并对其形态?粒径?包封率?加速实验结果及体外释放规律进行考察?【结果】 制得的哌仑西平脂质体为单层脂质体,平均粒径为480 nm,包封率为77.24%±9.83%,其稳定性好,缓释效果优于哌仑西平磷酸缓冲液?【结论】 哌仑西平脂质体达到设计要求? |
| format | Article |
| id | doaj-art-eee099c539884f5a82dd443c69694356 |
| institution | Kabale University |
| issn | 1672-3554 |
| language | zho |
| publishDate | 2004-01-01 |
| publisher | Editorial Office of Journal of Sun Yat-sen University |
| record_format | Article |
| series | Zhongshan Daxue xuebao. Yixue kexue ban |
| spelling | doaj-art-eee099c539884f5a82dd443c696943562025-01-15T03:26:34ZzhoEditorial Office of Journal of Sun Yat-sen UniversityZhongshan Daxue xuebao. Yixue kexue ban1672-35542004-01-012543585430哌仑西平脂质体的研制及评价戴淑真【目的】 制备稳定性好?包封率高?缓释性能优的哌仑西平脂质体?【方法】采用均匀设计等方法筛选制备哌仑西平脂质体的处方和工艺,并对其形态?粒径?包封率?加速实验结果及体外释放规律进行考察?【结果】 制得的哌仑西平脂质体为单层脂质体,平均粒径为480 nm,包封率为77.24%±9.83%,其稳定性好,缓释效果优于哌仑西平磷酸缓冲液?【结论】 哌仑西平脂质体达到设计要求?http://xuebaoyx.sysu.edu.cn/zh/article/43585430/ |
| spellingShingle | 戴淑真 哌仑西平脂质体的研制及评价 Zhongshan Daxue xuebao. Yixue kexue ban |
| title | 哌仑西平脂质体的研制及评价 |
| title_full | 哌仑西平脂质体的研制及评价 |
| title_fullStr | 哌仑西平脂质体的研制及评价 |
| title_full_unstemmed | 哌仑西平脂质体的研制及评价 |
| title_short | 哌仑西平脂质体的研制及评价 |
| title_sort | 哌仑西平脂质体的研制及评价 |
| url | http://xuebaoyx.sysu.edu.cn/zh/article/43585430/ |
| work_keys_str_mv | AT dàishūzhēn pàilúnxīpíngzhīzhìtǐdeyánzhìjípíngjià |