Synthesis of extended fluorinated tripeptides based on the tetrahydropyridazine scaffold
The synthesis of tripeptides incorporating new fluorinated heterocyclic hydrazino acids, based on the tetrahydropyridazine scaffold is described. Starting from simple fluorinated hydrazones, these non-proteinogenic cyclic β-amino acids were easily prepared by a zinc-catalyzed aza-Barbier reaction fo...
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Main Authors: | Thierry Milcent, Pascal Retailleau, Benoit Crousse, Sandrine Ongeri |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2024-12-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.20.262 |
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