Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort

Purpose The Lifelines COVID-19 cohort was set up to assess the psychological and societal impacts of the COVID-19 pandemic and investigate potential risk factors for COVID-19 within the Lifelines prospective population cohort.Participants Participants were recruited from the 140 000 eligible partici...

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Main Authors: Judith M Vonk, H Marike Boezen, Sandra Brouwer, Cisca Wijmenga, Ute Bültmann, Jochen Mierau, Johanna C Herkert, Alexandra Zhernakova, Katherine Mc Intyre, Pauline Lanting, Patrick Deelen, Henry H Wiersma, Anil P S Ori, Soesma A Jankipersadsing, Robert Warmerdam, Irene van Blokland, Floranne Boulogne, Marjolein X L Dijkema, Annique Claringbould, Olivier Bakker, Esteban A Lopera Maya, Sijmen A Reijneveld, Elianne Zijlstra, Morris A Swertz, Raun van Ooijen, Viola Angelini, Louise H Dekker, Anna Sijtsma, Sicco A Scherjon, Jackie A M Dekens, Lude Franke
Format: Article
Language:English
Published: BMJ Publishing Group 2021-03-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/3/e044474.full
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author Judith M Vonk
H Marike Boezen
Sandra Brouwer
Cisca Wijmenga
Ute Bültmann
Jochen Mierau
Johanna C Herkert
Alexandra Zhernakova
Katherine Mc Intyre
Pauline Lanting
Patrick Deelen
Henry H Wiersma
Anil P S Ori
Soesma A Jankipersadsing
Robert Warmerdam
Irene van Blokland
Floranne Boulogne
Marjolein X L Dijkema
Annique Claringbould
Olivier Bakker
Esteban A Lopera Maya
Sijmen A Reijneveld
Elianne Zijlstra
Morris A Swertz
Raun van Ooijen
Viola Angelini
Louise H Dekker
Anna Sijtsma
Sicco A Scherjon
Jackie A M Dekens
Lude Franke
author_facet Judith M Vonk
H Marike Boezen
Sandra Brouwer
Cisca Wijmenga
Ute Bültmann
Jochen Mierau
Johanna C Herkert
Alexandra Zhernakova
Katherine Mc Intyre
Pauline Lanting
Patrick Deelen
Henry H Wiersma
Anil P S Ori
Soesma A Jankipersadsing
Robert Warmerdam
Irene van Blokland
Floranne Boulogne
Marjolein X L Dijkema
Annique Claringbould
Olivier Bakker
Esteban A Lopera Maya
Sijmen A Reijneveld
Elianne Zijlstra
Morris A Swertz
Raun van Ooijen
Viola Angelini
Louise H Dekker
Anna Sijtsma
Sicco A Scherjon
Jackie A M Dekens
Lude Franke
author_sort Judith M Vonk
collection DOAJ
description Purpose The Lifelines COVID-19 cohort was set up to assess the psychological and societal impacts of the COVID-19 pandemic and investigate potential risk factors for COVID-19 within the Lifelines prospective population cohort.Participants Participants were recruited from the 140 000 eligible participants of Lifelines and the Lifelines NEXT birth cohort, who are all residents of the three northern provinces of the Netherlands. Participants filled out detailed questionnaires about their physical and mental health and experiences on a weekly basis starting in late March 2020, and the cohort consists of everyone who filled in at least one questionnaire in the first 8 weeks of the project.Findings to date >71 000 unique participants responded to the questionnaires at least once during the first 8 weeks, with >22 000 participants responding to seven questionnaires. Compiled questionnaire results are continuously updated and shared with the public through the Corona Barometer website. Early results included a clear signal that younger people living alone were experiencing greater levels of loneliness due to lockdown, and subsequent results showed the easing of anxiety as lockdown was eased in June 2020.Future plans Questionnaires were sent on a (bi)weekly basis starting in March 2020 and on a monthly basis starting July 2020, with plans for new questionnaire rounds to continue through 2020 and early 2021. Questionnaire frequency can be increased again for subsequent waves of infections. Cohort data will be used to address how the COVID-19 pandemic developed in the northern provinces of the Netherlands, which environmental and genetic risk factors predict disease susceptibility and severity and the psychological and societal impacts of the crisis. Cohort data are linked to the extensive health, lifestyle and sociodemographic data held for these participants by Lifelines, a 30-year project that started in 2006, and to data about participants held in national databases.
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spelling doaj-art-eea6f2f8ba31490abd6efec75d8d475a2024-11-21T00:20:09ZengBMJ Publishing GroupBMJ Open2044-60552021-03-0111310.1136/bmjopen-2020-044474Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohortJudith M Vonk0H Marike Boezen1Sandra Brouwer2Cisca Wijmenga3Ute Bültmann4Jochen Mierau5Johanna C Herkert6Alexandra Zhernakova7Katherine Mc Intyre8Pauline Lanting9Patrick Deelen10Henry H Wiersma11Anil P S Ori12Soesma A Jankipersadsing13Robert Warmerdam14Irene van Blokland15Floranne Boulogne16Marjolein X L Dijkema17Annique Claringbould18Olivier Bakker19Esteban A Lopera Maya20Sijmen A Reijneveld21Elianne Zijlstra22Morris A Swertz23Raun van Ooijen24Viola Angelini25Louise H Dekker26Anna Sijtsma27Sicco A Scherjon28Jackie A M Dekens29Lude Franke30Department of Epidemiology, University of Groningen, University Medical Center, Groningen, The Netherlands1 University Medical Center Groningen, Department of Epidemiology, University of Groningen, Groningen, Netherlands6 Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2 Health Sciences, Community and Occupational Medicine, University of Groningen, Groningen, Netherlands7 Faculty of Economics and Business, University of Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands2 University Medical Centre, Groningen, Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands6 Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands6 Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands6 Department of Health Sciences, Community and Occupational Medicine, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsFaculty of Economics and Business, University of Groningen, Groningen, The Netherlands7 Faculty of Economics and Business, University of Groningen, Groningen, The NetherlandsLifelines Cohort Study, University Medical Centre Groningen, Groningen, The Netherlands10 Department of Obstetrics and Gynaecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands1 Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The NetherlandsPurpose The Lifelines COVID-19 cohort was set up to assess the psychological and societal impacts of the COVID-19 pandemic and investigate potential risk factors for COVID-19 within the Lifelines prospective population cohort.Participants Participants were recruited from the 140 000 eligible participants of Lifelines and the Lifelines NEXT birth cohort, who are all residents of the three northern provinces of the Netherlands. Participants filled out detailed questionnaires about their physical and mental health and experiences on a weekly basis starting in late March 2020, and the cohort consists of everyone who filled in at least one questionnaire in the first 8 weeks of the project.Findings to date >71 000 unique participants responded to the questionnaires at least once during the first 8 weeks, with >22 000 participants responding to seven questionnaires. Compiled questionnaire results are continuously updated and shared with the public through the Corona Barometer website. Early results included a clear signal that younger people living alone were experiencing greater levels of loneliness due to lockdown, and subsequent results showed the easing of anxiety as lockdown was eased in June 2020.Future plans Questionnaires were sent on a (bi)weekly basis starting in March 2020 and on a monthly basis starting July 2020, with plans for new questionnaire rounds to continue through 2020 and early 2021. Questionnaire frequency can be increased again for subsequent waves of infections. Cohort data will be used to address how the COVID-19 pandemic developed in the northern provinces of the Netherlands, which environmental and genetic risk factors predict disease susceptibility and severity and the psychological and societal impacts of the crisis. Cohort data are linked to the extensive health, lifestyle and sociodemographic data held for these participants by Lifelines, a 30-year project that started in 2006, and to data about participants held in national databases.https://bmjopen.bmj.com/content/11/3/e044474.full
spellingShingle Judith M Vonk
H Marike Boezen
Sandra Brouwer
Cisca Wijmenga
Ute Bültmann
Jochen Mierau
Johanna C Herkert
Alexandra Zhernakova
Katherine Mc Intyre
Pauline Lanting
Patrick Deelen
Henry H Wiersma
Anil P S Ori
Soesma A Jankipersadsing
Robert Warmerdam
Irene van Blokland
Floranne Boulogne
Marjolein X L Dijkema
Annique Claringbould
Olivier Bakker
Esteban A Lopera Maya
Sijmen A Reijneveld
Elianne Zijlstra
Morris A Swertz
Raun van Ooijen
Viola Angelini
Louise H Dekker
Anna Sijtsma
Sicco A Scherjon
Jackie A M Dekens
Lude Franke
Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort
BMJ Open
title Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort
title_full Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort
title_fullStr Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort
title_full_unstemmed Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort
title_short Lifelines COVID-19 cohort: investigating COVID-19 infection and its health and societal impacts in a Dutch population-based cohort
title_sort lifelines covid 19 cohort investigating covid 19 infection and its health and societal impacts in a dutch population based cohort
url https://bmjopen.bmj.com/content/11/3/e044474.full
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