Screening of Aβ and phosphorylated tau status in the cerebrospinal fluid through machine learning analysis of portable electroencephalography data

Screening of Aβ and phosphorylated tau status in the cerebrospinal fluid through machine learning analysis of portable electroencephalography data

Abstract Diagnosing Alzheimer’s disease (AD) through pathological markers is typically costly and invasive. This study aims to find a noninvasive, cost-effective method using portable electroencephalography (EEG) to detect changes in AD-related biomarkers in cerebrospinal fluid (CSF). A total of 102...

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Main Authors: Masahiro Hata, Yuki Miyazaki, Kohji Mori, Kenji Yoshiyama, Shoshin Akamine, Hideki Kanemoto, Shiho Gotoh, Hisaki Omori, Atsuya Hirashima, Yuto Satake, Takashi Suehiro, Shun Takahashi, Manabu Ikeda
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Dementia
EEG
Alzheimer’s disease
Amyloid beta
Phosphorylated tau
Machine learning
Online Access:https://doi.org/10.1038/s41598-025-86449-2
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