Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness

Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness

BackgroundThis study investigated the protective role and mechanisms of hyperbaric oxygen (HBO) pretreatment in enhancing vascular endothelial cell (VEC) resistance to bubble-induced injury by focusing on heat shock factor 1 (HSF-1) to prevent decompression sickness (DCS).MethodsPrimary cultured rat...

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Bibliographic Details
Main Authors:	Caiyi Xu, Quan Zhou, Xiangyang Meng, Jiahe Zhou, Xuhua Yu, Juan Zheng, Hongjie Yi, Guoyang Huang, Weigang Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Molecular Biosciences
Subjects:	decompression sickness hyperbaric oxygen heat shock factor 1 pulmonary microvascular endothelial cells protective protein
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2025.1617318/full
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