Evaluation of gait speed over time in adults with arthritis: Data from the osteoarthritis initiative
Objective: In this longitudinal study across four clinical sites in the United States, gait speed (GS) over time in adults with arthritis was examined. Methods: We performed a secondary analysis using data from the osteoarthritis initiative. A sample of 4450 adults aged 45 years and older, regardles...
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SAGE Publishing
2018-01-01
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| Series: | Indian Journal of Rheumatology |
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| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2018;volume=13;issue=3;spage=154;epage=158;aulast=Vennu |
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| _version_ | 1841561367510777856 |
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| author | Vishal Vennu Harsh Misra |
| author_facet | Vishal Vennu Harsh Misra |
| author_sort | Vishal Vennu |
| collection | DOAJ |
| description | Objective: In this longitudinal study across four clinical sites in the United States, gait speed (GS) over time in adults with arthritis was examined.
Methods: We performed a secondary analysis using data from the osteoarthritis initiative. A sample of 4450 adults aged 45 years and older, regardless of sex or ethnicity, were included in the analysis. Based on the response to self-reported questionnaires about arthritis, adults were classified into two groups: without arthritis and with arthritis. GS in m/s was assessed using the 20-m-walk test at baseline and over time. A general linear mixed model was used to examine the GS over time in adults with arthritis.
Results: The rate of decrease in GS per year was 0.006 m/s after adjusting for age, sex, race, depressive symptoms, and body mass index. In adults, having arthritis was significantly associated with lower GS (β = −0.039, standard error = 0.007, P <.001) compared to those without arthritis. The interaction between arthritis, GS, and time was also significant (β = −0.0013, SE = 0.005, P = 0.017), indicating that the slope changed over time due to the continuous decline in GS (0.006 m/s/year).
Conclusions: In adults, having arthritis is associated with lower GS and declined over time compared to those without arthritis, even after controlling for all covariates. |
| format | Article |
| id | doaj-art-ee1004eaef94447c8bcb97be78442809 |
| institution | Kabale University |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-ee1004eaef94447c8bcb97be784428092025-01-03T01:45:39ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012018-01-0113315415810.4103/injr.injr_34_18Evaluation of gait speed over time in adults with arthritis: Data from the osteoarthritis initiativeVishal VennuHarsh MisraObjective: In this longitudinal study across four clinical sites in the United States, gait speed (GS) over time in adults with arthritis was examined. Methods: We performed a secondary analysis using data from the osteoarthritis initiative. A sample of 4450 adults aged 45 years and older, regardless of sex or ethnicity, were included in the analysis. Based on the response to self-reported questionnaires about arthritis, adults were classified into two groups: without arthritis and with arthritis. GS in m/s was assessed using the 20-m-walk test at baseline and over time. A general linear mixed model was used to examine the GS over time in adults with arthritis. Results: The rate of decrease in GS per year was 0.006 m/s after adjusting for age, sex, race, depressive symptoms, and body mass index. In adults, having arthritis was significantly associated with lower GS (β = −0.039, standard error = 0.007, P <.001) compared to those without arthritis. The interaction between arthritis, GS, and time was also significant (β = −0.0013, SE = 0.005, P = 0.017), indicating that the slope changed over time due to the continuous decline in GS (0.006 m/s/year). Conclusions: In adults, having arthritis is associated with lower GS and declined over time compared to those without arthritis, even after controlling for all covariates.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2018;volume=13;issue=3;spage=154;epage=158;aulast=VennuAdultsAfrican Americanarthritisbody mass indexdepression |
| spellingShingle | Vishal Vennu Harsh Misra Evaluation of gait speed over time in adults with arthritis: Data from the osteoarthritis initiative Indian Journal of Rheumatology Adults African American arthritis body mass index depression |
| title | Evaluation of gait speed over time in adults with arthritis: Data from the osteoarthritis initiative |
| title_full | Evaluation of gait speed over time in adults with arthritis: Data from the osteoarthritis initiative |
| title_fullStr | Evaluation of gait speed over time in adults with arthritis: Data from the osteoarthritis initiative |
| title_full_unstemmed | Evaluation of gait speed over time in adults with arthritis: Data from the osteoarthritis initiative |
| title_short | Evaluation of gait speed over time in adults with arthritis: Data from the osteoarthritis initiative |
| title_sort | evaluation of gait speed over time in adults with arthritis data from the osteoarthritis initiative |
| topic | Adults African American arthritis body mass index depression |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2018;volume=13;issue=3;spage=154;epage=158;aulast=Vennu |
| work_keys_str_mv | AT vishalvennu evaluationofgaitspeedovertimeinadultswitharthritisdatafromtheosteoarthritisinitiative AT harshmisra evaluationofgaitspeedovertimeinadultswitharthritisdatafromtheosteoarthritisinitiative |