A study for the genotoxicity assessment of substances containing probiotic candidates in the in vitro TK6 cell micronucleus test: Influence of low pH conditions and antibiotic supplementation on the test results

Abstract Background When assessing the genotoxicity of substances containing probiotic candidates, such as lactic acid-producing bacteria, using the in vitro micronucleus test (MNT), bacterial growth in the test medium may reduce the pH of the medium. The low medium pH is known to induce cytotoxicit...

Full description

Saved in:
Bibliographic Details
Main Authors: Yohei Fujiishi, Wakako Ohyama, Emiko Okada
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Genes and Environment
Subjects:
Online Access:https://doi.org/10.1186/s41021-024-00320-w
Tags: Add Tag
No Tags, Be the first to tag this record!