Inflammatory synergy: a rare encounter of eosinophilic esophagitis and acute gastritis
Eosinophilic Esophagitis (EoE) is a chronic, antigen-mediated esophageal disease characterized by eosinophil predominant inflammation, typically identified in younger individuals, particularly white males between 30 and 40 years of age. However, this case report discusses an unusual presentation of...
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2024-09-01
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| Series: | Romanian Journal of Medical Practice |
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| Online Access: | https://rjmp.com.ro/articles/2024.3/RJMP_2024_3_Art-14.pdf |
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| author | V. PRIYADHARSHINI K.I.S.N. VAISHNAVI N. Krishna GEETHA Shankar A. GOWRI |
| author_facet | V. PRIYADHARSHINI K.I.S.N. VAISHNAVI N. Krishna GEETHA Shankar A. GOWRI |
| author_sort | V. PRIYADHARSHINI |
| collection | DOAJ |
| description | Eosinophilic Esophagitis (EoE) is a chronic, antigen-mediated esophageal disease characterized by eosinophil predominant inflammation, typically identified in younger individuals, particularly white males between 30 and 40 years of age. However, this case report discusses an unusual presentation of EoE in a 65-year old female with a history of allergic rhinitis. The patient presented with symptoms of heartburn, epigastric pain, dysphagia, nausea, vomiting, and abdominal bloating, which had been occurring intermittently over the past two years. Investigations revealed significant eosinophilia, with 20% eosinophils in the differential count and a high erythrocyte sedimentation rate (ESR) of 34 mm/hr. Endoscopy demonstrated feline esophagus with unhealthy mucosa in the lower esophagus and an inflamed, edematous antrum. Biopsies confirmed the diagnosis of EoE with 18 eosinophils per high-power field. This case highlights the importance of considering EoE in elderly patients presenting with gastrointestinal symptoms, particularly in those with a history of atopic conditions. Early diagnosis and treatment are crucial in managing symptoms and preventing complications. |
| format | Article |
| id | doaj-art-edb59d8631aa4cb4ace4b6ec734b9919 |
| institution | Kabale University |
| issn | 1842-8258 2069-6108 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Medical Practice |
| spelling | doaj-art-edb59d8631aa4cb4ace4b6ec734b99192024-12-19T15:06:06ZengAmaltea Medical Publishing HouseRomanian Journal of Medical Practice1842-82582069-61082024-09-0119330130510.37897/RJMP.2024.3.14Inflammatory synergy: a rare encounter of eosinophilic esophagitis and acute gastritisV. PRIYADHARSHINI0K.I.S.N. VAISHNAVI1N. Krishna GEETHA2Shankar A. GOWRI3Department of General Medicine, Saveetha Medical College, Chennai, Tamil Nadu, IndiaDepartment of General Medicine, Saveetha Medical College, Chennai, Tamil Nadu, IndiaDepartment of General Medicine, Saveetha Medical College, Chennai, Tamil Nadu, IndiaDepartment of General Medicine, Saveetha Medical College, Chennai, Tamil Nadu, IndiaEosinophilic Esophagitis (EoE) is a chronic, antigen-mediated esophageal disease characterized by eosinophil predominant inflammation, typically identified in younger individuals, particularly white males between 30 and 40 years of age. However, this case report discusses an unusual presentation of EoE in a 65-year old female with a history of allergic rhinitis. The patient presented with symptoms of heartburn, epigastric pain, dysphagia, nausea, vomiting, and abdominal bloating, which had been occurring intermittently over the past two years. Investigations revealed significant eosinophilia, with 20% eosinophils in the differential count and a high erythrocyte sedimentation rate (ESR) of 34 mm/hr. Endoscopy demonstrated feline esophagus with unhealthy mucosa in the lower esophagus and an inflamed, edematous antrum. Biopsies confirmed the diagnosis of EoE with 18 eosinophils per high-power field. This case highlights the importance of considering EoE in elderly patients presenting with gastrointestinal symptoms, particularly in those with a history of atopic conditions. Early diagnosis and treatment are crucial in managing symptoms and preventing complications.https://rjmp.com.ro/articles/2024.3/RJMP_2024_3_Art-14.pdfeosinophilic esophagitisacute gastritiseosinophiliagastroesophageal reflux disease |
| spellingShingle | V. PRIYADHARSHINI K.I.S.N. VAISHNAVI N. Krishna GEETHA Shankar A. GOWRI Inflammatory synergy: a rare encounter of eosinophilic esophagitis and acute gastritis Romanian Journal of Medical Practice eosinophilic esophagitis acute gastritis eosinophilia gastroesophageal reflux disease |
| title | Inflammatory synergy: a rare encounter of eosinophilic esophagitis and acute gastritis |
| title_full | Inflammatory synergy: a rare encounter of eosinophilic esophagitis and acute gastritis |
| title_fullStr | Inflammatory synergy: a rare encounter of eosinophilic esophagitis and acute gastritis |
| title_full_unstemmed | Inflammatory synergy: a rare encounter of eosinophilic esophagitis and acute gastritis |
| title_short | Inflammatory synergy: a rare encounter of eosinophilic esophagitis and acute gastritis |
| title_sort | inflammatory synergy a rare encounter of eosinophilic esophagitis and acute gastritis |
| topic | eosinophilic esophagitis acute gastritis eosinophilia gastroesophageal reflux disease |
| url | https://rjmp.com.ro/articles/2024.3/RJMP_2024_3_Art-14.pdf |
| work_keys_str_mv | AT vpriyadharshini inflammatorysynergyarareencounterofeosinophilicesophagitisandacutegastritis AT kisnvaishnavi inflammatorysynergyarareencounterofeosinophilicesophagitisandacutegastritis AT nkrishnageetha inflammatorysynergyarareencounterofeosinophilicesophagitisandacutegastritis AT shankaragowri inflammatorysynergyarareencounterofeosinophilicesophagitisandacutegastritis |